An Exploratory Study of Two Caco-2 Cell Models for Oral Absorption: A Report on Their Within-laboratory and Between-laboratory Variability, and Their Predictive Capacity
- Author
- PRIETO, Pilar1 ; HOFFMANN, Sebastian2 ; TIRELLI, Valentina3 ; TANCREDI, Francesco3 ; GONZALEZ, Isabel4 ; BERMEJO, Marival4 ; DE ANGELIS, Isabella3
[1] In Vitro Methods Unit/European Centre for the Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy
[2] seh consulting + services, Cologne, Germany
[3] Department of Environmental and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy
[4] Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Valencia, Spain - Source
ATLA. Alternatives to laboratory animals. 2010, Vol 38, Num 5, pp 367-386, 20 p ; ref : 47 ref
- ISSN
- 0261-1929
- Scientific domain
- Medical laboratory techniques; Toxicology
- Publisher
- Fund for the Replacement of Animals in Medical Experiments, Nottingham
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Caco-2/TC7 Caco-2 intestinal absorption prediction model prevalidation
- Keyword (fr)
- Facteur prédictif In vitro Intestin Laboratoire Modèle Méthode alternative Prédiction Variabilité Absorption intestinale Lignée CACO2 Appareil digestif Côlon Homme Lignée cellulaire
- Keyword (en)
- Predictive factor In vitro Gut Laboratory Models Alternative method Prediction Variability Intestinal absorption Digestive system Colon Human Cell line
- Keyword (es)
- Factor predictivo In vitro Intestino Laboratorio Modelo Método alternativo Predicción Variabilidad Aparato digestivo Colón Hombre Línea celular
- Classification
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23529443
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1177/026119291003800510 
https://dx.doi.org/10.1177/026119291003800510
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