Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile
- Author
- MARTINELLI, Nicola1 ; GIRELLI, Domenico1 ; LUNGHI, Barbara2 ; PINOTTI, Mirko2 ; MARCHETTI, Giovanna2 ; MALERBA, Giovanni3 ; FRANCO PIGNATTI, Pier3 ; CORROCHER, Roberto1 ; OLIVIERI, Oliviero1 ; BERNARDI, Francesco2
[1] Department of Medicine, University of Verona, Verona, Italy
[2] Department of Biochemistry and Molecular Biology, University of Ferrara, Ferrara, Italy
[3] Department of Sciences of Life and Reproduction, University of Verona, Verona, Italy - Source
Blood. 2010, Vol 116, Num 25, pp 5688-5697, 10 p ; ref : 49 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Cardiopathie coronaire Facteur antihémophilique A Facteur coagulation Génotype Hématologie Lipide Locus Modulation Polymorphisme Variabilité génétique Pathologie de l'appareil circulatoire
- Keyword (en)
- Biological activity Coronary heart disease Factor VIII Coagulation factor Genotype Hematology Lipids Locus Modulation Polymorphism Genetic variability Cardiovascular disease
- Keyword (es)
- Actividad biológica Cardiopatía coronaria Factor antihemofílico A Factor coagulación Genotipo Hematología Lípido Locus Modulación Polimorfismo Variabilidad genética Aparato circulatorio patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A03 Coronary heart disease
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases
- Discipline
- Blood diseases Cardiology. Circulatory system
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23686203
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2010-03-277079 
https://dx.doi.org/10.1182/blood-2010-03-277079
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