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PI3K/Akt/mTOR Pathway Inhibitors in Cancer: A Perspective on Clinical Progress

Author
WU, P1 ; HU, Y.-Z1
[1] ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
Source

Current medicinal chemistry. 2010, Vol 17, Num 35, pp 4326-4341, 16 p ; ref : 111 ref

ISSN
0929-8673
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Bentham, Oak Park, IL
Publication country
United States
Document type
Article
Language
English
Author keyword
Akt/PKB PI3K cancer clinical mTOR small-molecule inhibitor
Keyword (fr)
1-Phosphatidylinositol 3-kinase Akt protein kinase Anticancéreux Essai clinique Hétérocycle azote Inhibiteur Molécule petite Non-specific serine/threonine protein kinase Perspective Protéine mTOR Recherche et développement Transduction signal Tumeur maligne Cancer Enzyme Transferases
Keyword (en)
1-Phosphatidylinositol 3-kinase Akt protein kinase Antineoplastic agent Clinical trial Nitrogen heterocycle Inhibitor Small molecule Non-specific serine/threonine protein kinase Perspective Mammalian target of rapamycin Research and development Signal transduction Malignant tumor Cancer Enzyme Transferases
Keyword (es)
1-Phosphatidylinositol 3-kinase Akt protein kinase Anticanceroso Ensayo clínico Heterociclo nitrógeno Inhibidor Molécula pequeña Non-specific serine/threonine protein kinase Perspectiva Proteína mTOR Investigación desarrollo Transducción señal Tumor maligno Cáncer Enzima Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
23692924

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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