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Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints

Author
WANG, Hui-Min1 ; CHENG, Kuo-Chen2 ; LIN, Cheng-Jung3 4 ; HSU, Shu-Wei4 ; FANG, Wei-Cheng4 ; HSU, Tai-Feng4 ; CHIU, Chien-Chih3 ; CHANG, Hsueh-Wei5 ; HSU, Chun-Hua6 ; LEE, Alan Yueh-Luen4
[1] Department of Fragrance and Cosmetic Science, Kaohsiung Medical University, Kaohsiung, Taiwan, Province of China
[2] Department of Intensive Care Medicine, Chi-Mei Medical Centre, Tainan, Taiwan, Province of China
[3] Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan, Province of China
[4] National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, Taiwan, Province of China
[5] Biomedical Science and Environmental Biology and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Province of China
[6] Department of Agricultural Chemistry, National Taiwan University, Taipei, Taiwan, Province of China
Source

Cancer science. 2010, Vol 101, Num 12, pp 2612-2620, 9 p ; ref : 45 ref

ISSN
1347-9032
Scientific domain
Medical oncology
Publisher
Blackwell, Richmond
Publication country
Australia
Document type
Article
Language
English
Keyword (fr)
Apoptose Cancer du poumon Cancérologie Cellule tumorale DNA mitochondrial Homme Lésion Mort cellulaire Peptidases Point contrôle Cancer Enzyme Hydrolases Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Tumeur maligne
Keyword (en)
Apoptosis Lung cancer Cancerology Tumor cell Mitochondrial DNA Human Lesion Cell death Peptidases Control point Cancer Enzyme Hydrolases Respiratory disease Bronchus disease Lung disease Malignant tumor
Keyword (es)
Apoptosis Cáncer del pulmón Cancerología Célula tumoral DNA mitocondrial Hombre Lesión Muerte celular Peptidases Punto control Cáncer Enzima Hydrolases Aparato respiratorio patología Bronquio patología Pulmón patología Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum

Discipline
Pulmonology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
23716027

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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