A multi-centre longitudinal study comparing the sensitivity of monthly MRI after standard and triple dose gadolinium-DTPA for monitoring disease activity in multiple sclerosis implications for phase II clinical trials
- Author
- FILIPPI, M1 ; ROVARIS, M1 ; KÜHNE, I4 ; POZZILLI, C3 ; COMI, G8 ; CAPRA, R2 ; GASPERINI, C3 ; YOUSRY, T. A4 ; SORMANI, M. P1 5 ; PRANDINI, F6 ; HORSFIELD, M. A7 ; MARTINELLI, V8 ; BASTIANELLO, S9
[1] Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute, Ospedale San Raffaele, University of Milan, Milan, Italy
[2] Department of Neurology, Spedali Sivili, University of Brescia, Brescia, Italy
[3] Department of Neurology, Università ' La Sapienza', Rome, Italy
[4] Department of Neuroradiology, Klinikum Grosshadern, University of Munich, Munich, Germany
[5] Department of Clinical Epidemiology and Trials, National Institute for Cancer Research, Genoa, Italy
[6] Department of Neuroradiology, Spedali Civili, University of Brescia, Brescia, Italy
[7] Division of Medical Physics, University of Leicester, Leicester, United Kingdom
[8] Unit of Clinical Trials, Department of Neuroscience, Scientific Institute, Ospedale San Raffaele, University of Milan, Milan, Italy
[9] Department of Neuroradiology, Università ' La Sapienza', Rome, Italy - Source
Brain. 1998, Vol 121, pp 2011-2020 ; 10 ; ref : 1 p.3/4
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Dose Encéphale Essai clinique phase II Etude comparative Etude longitudinale Etude multicentrique Exploration Gadolinium Homme Imagerie RMN Produit contraste Sclérose en plaque Technique Imagerie médicale Maladie inflammatoire Système nerveux central pathologie Système nerveux central Système nerveux pathologie
- Keyword (en)
- Dose Brain (vertebrata) Phase II trial Comparative study Follow up study Multicenter study Exploration Gadolinium Human Nuclear magnetic resonance imaging Contrast media Multiple sclerosis Technique Medical imagery Inflammatory disease Central nervous system disease Central nervous system Nervous system diseases
- Keyword (es)
- Dosis Encéfalo Ensayo clínico fase II Estudio comparativo Estudio longitudinal Estudio multicéntrico Exploración Gadolinio Hombre Imageria RMN Medio contraste Esclerosis en placa Técnica Imageneria medical Enfermedad inflamatoria Sistema nervosio central patología Sistema nervioso central Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17F Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2409215
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/brain/121.10.2011 
https://dx.doi.org/10.1093/brain/121.10.2011
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