Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma
- Author
- SANTISKULVONG, Chintda1 ; KONECNY, Gottfried E2 ; FEKETE, Mirela1 ; CHEN, Kuang-Yui Michael1 ; KARAM, Amer1 ; MULHOLLAND, David3 ; ENG, Carol1 ; HONG WU3 ; MIN SONG1 ; DORIGO, Oliver1
[1] Division of Gynecologic Oncology, UCLA David Geffen School of Medicine, Los Angeles, CA, United States
[2] Department of Obstetrics and Gynecology, UCLA David Geffen School of Medicine, Los Angeles, CA, United States
[3] Department of Hematology/Oncology, and Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, CA, United States - Source
Clinical cancer research (Print). 2011, Vol 17, Num 8, pp 2373-2384, 12 p ; ref : 49 ref
- CODEN
- CCREF4
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Anticancéreux Cancer de l'ovaire Carcinome de l'ovaire Ciblage Cible Homme Protéine mTOR Sirolimus Traitement Inhibiteur mTOR Cancer Enzyme Inhibiteur synthèse protéique Lactone Macrocycle Macrolide Pathologie de l'appareil génital femelle Pathologie des ovaires Transferases Tumeur maligne
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Antineoplastic agent Ovary cancer Ovary carcinoma Targeting Target Human Mammalian target of rapamycin Sirolimus Treatment Cancer Enzyme Protein synthesis inhibitor Lactone Macrocycle Macrolide Female genital diseases Ovarian diseases Transferases Malignant tumor
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Anticanceroso Cáncer del ovario Carcinoma de ovario Blancado Blanco Hombre Proteína mTOR Sirolimús Tratamiento Cáncer Enzima Inhibidor síntesis proteica Lactona Macrociclo Macrólido Aparato genital hembra patología Ovario patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20C Female genital diseases / 002B20C02 Tumors
- Discipline
- Gynecology. Andrology. Obstetrics Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24123212
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-10-2289 
https://dx.doi.org/10.1158/1078-0432.CCR-10-2289
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