Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting
- Author
- JIZHONG ZOU1 ; SWEENEY, Colin L2 ; CHOU, Bin-Kuan1 3 ; CHOI, Uimook2 ; PAN, Jason2 ; HONGMEI WANG2 ; DOWEY, Sarah N1 ; LINZHAO CHENG1 3 ; MALECH, Harry L2
[1] Division of Hematology, Department of Medicine, and Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States
[2] Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States
[3] Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States - Source
Blood. 2011, Vol 117, Num 21, pp 5561-5572, 12 p ; ref : 37 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Caractère lié au sexe Chromosome X Ciblage Granulocyte Granulomatose chronique Hématologie Neutrophile Nuclease Oxidase Structure doigt zinc Enzyme Esterases Hydrolases Hémopathie Immunodéficit Immunopathologie Maladie des leucocytes Maladie héréditaire Oxidoreductases
- Keyword (en)
- Sex linked character X-Chromosome Targeting Granulocyte Chronic granulomatous disease Hematology Neutrophil Nuclease Oxidase Zinc finger structure Enzyme Esterases Hydrolases Hemopathy Immune deficiency Immunopathology Leukocyte disease Genetic disease Oxidoreductases
- Keyword (es)
- Carácter ligado al sexo Cromosoma X Blancado Granulocito Enfermedad granulomatosa crónica Hematología Neutrófilo Nuclease Oxidase Estructura dedo zinc Enzima Esterases Hydrolases Hemopatía Inmunodeficiencia Inmunopatología Leucocito enfermedad Enfermedad hereditaria Oxidoreductases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology / 002B06D Immunodeficiencies. Immunoglobulinopathies / 002B06D01 Immunodeficiencies
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19D Other diseases. Hematologic involvement in other diseases
- Discipline
- Blood diseases Immunopathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24203834
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2010-12-328161 
https://dx.doi.org/10.1182/blood-2010-12-328161
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