Pharmacophore based virtual screening, molecular docking studies to design potent heat shock protein 90 inhibitors
- Author
- SAKKIAH, Sugunadevi1 ; THANGAPANDIAN, Sundarapandian1 ; JOHN, Shalini1 ; KEUN WOO LEE1
[1] Division of Applied Life Science (BK21 Program), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Department of Chemistry and Research Institute, Gyeongsang National University (GNU), 900 Gazwa-dong, Jinju 660-701, Korea, Republic of - Source
European journal of medicinal chemistry. 2011, Vol 46, Num 7, pp 2937-2947, 11 p ; ref : 55 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Common feature hypothesis GOLD Heat shock protein 90 LigandScout Structure-based pharmacophore Virtual screening
- Keyword (fr)
- Adenosinetriphosphatase Chaperon Complexe enzyme inhibiteur Criblage virtuel Inhibiteur enzyme Modèle moléculaire Modélisation Protéine choc thermique Protéine de choc thermique 90 Relation structure activité Transduction signal Pharmacophore Enzyme Hydrolases
- Keyword (en)
- Adenosinetriphosphatase Chaperone Inhibitor enzyme complex Virtual screening Enzyme inhibitor Molecular model Modeling Heat shock protein Heat shock protein 90 Structure activity relation Signal transduction Enzyme Hydrolases
- Keyword (es)
- Adenosinetriphosphatase Chaperone Complejo enzima inhibidor Cribado virtual Inhibidor enzima Modelo molecular Modelización Proteína choque térmico Proteína de choque térmico 90 Relación estructura actividad Transducción señal Enzima Hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24227159
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2011.04.018 
https://dx.doi.org/10.1016/j.ejmech.2011.04.018
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