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Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway

Author
LEE, Ko-Chen1 2 3 ; CHANG, Hen-Hong1 2 3 ; CHUNG, Ying-Hui2 3 ; LEE, Tzung-Yan2
[1] Graduate Institute of Clinical Medicine Science, Chang Gung University, Taoyuan, Taiwan, Province of China
[2] Graduate Institute of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan, Province of China
[3] Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, Province of China
Source

Journal of ethnopharmacology. 2011, Vol 135, Num 3, pp 678-684, 7 p ; ref : 3/4 p

CODEN
JOETD7
ISSN
0378-8741
Scientific domain
Social anthropology and ethnology; Pharmacology drugs
Publisher
Elsevier, Shannon
Publication country
Ireland
Document type
Article
Language
English
Author keyword
Andrographolide Apoptosis Inflammation NF-κB STAT3 iNOS
Keyword (fr)
Antiinflammatoire Apoptose Diterpène Dérivé du labdane Facteur transcription NFκB Inflammation Macrophage Mort cellulaire Nitric-oxide synthase Origine végétale Pharmacognosie Plante médicinale Terpénoïde Andrographolide Enzyme Oxidoreductases
Keyword (en)
Antiinflammatory agent Apoptosis Diterpene Labdane derivatives Transcription factor NFκB Inflammation Macrophage Cell death Nitric-oxide synthase Plant origin Pharmacognosy Medicinal plant Terpenoid Enzyme Oxidoreductases
Keyword (es)
Antiinflamatorio Apoptosis Diterpeno Labdano derivado Factor transcripción NFκB Inflamación Macrófago Muerte celular Nitric-oxide synthase Origen vegetal Farmacognosia Planta medicinal Terpenoide Enzima Oxidoreductases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24234339

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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