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Synthesis and evaluation of chromenyl barbiturates and thiobarbiturates as potential antitubercular agents

Author
VIJAYA LAXMI, S1 ; THIRUPATHI REDDY, Y2 ; SURESH KUARM, B1 ; NARSIMHA REDDY, P2 ; CROOKS, Peter A2 ; RAJITHA, B1
[1] Department of Chemistry, National Institute of Technology, Warangal 506 004, AP, India
[2] Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536-0082, United States
Source

Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 14, pp 4329-4331, 3 p ; ref : 17 ref

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Anti tuberculosis activity Barbituric acid Knoevenagel condensation Thiobarbituric acid
Keyword (fr)
Antibactérien Antituberculeux Barbituriques Composé tricyclique Condensation Knoevenagel Dérivé de la pyrimidine Dérivé du benzène Hétérocycle oxygène In vitro Lactone Mycobacterium tuberculosis Relation structure activité Synthèse chimique Barbiturique acide dérivé Benzo[1,2-b:5,4-b']dipyrane-2,6-dione dérivé Benzodipyrane Furo[3,2-g][1]benzopyran-5-one dérivé Furobenzopyrane Thiobarbiturique acide dérivé Actinomycetes Bactérie Mycobacteriaceae Mycobacteriales
Keyword (en)
Antibacterial agent Antituberculous agent Barbiturates Tricyclic compound Knoevenagel condensation Pyrimidine derivatives Benzene derivatives Oxygen heterocycle In vitro Lactone Mycobacterium tuberculosis Structure activity relation Chemical synthesis Actinomycetes Bacteria Mycobacteriaceae Mycobacteriales
Keyword (es)
Antibacteriano Antituberculoso Barbitúricos Compuesto tricíclico Condensación Knoevenage Pirimidina derivado Benceno derivado Heterociclo oxígeno In vitro Lactona Mycobacterium tuberculosis Relación estructura actividad Síntesis química Actinomycetes Bacteria Mycobacteriaceae Mycobacteriales
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24343643

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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