Targeting PDK1 in Cancer : Phosphoinositide 3-Kinase Pathway Inhibitors: Pharmacology, Metabolism and Drug Development
- Author
- RAIMONDI, C1 ; FALASCA, M1
[1] Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute of Cell and Molecular Science, Centre for Diabetes, Inositide Signalling Group, London E1 2AT, United Kingdom - Source
Current medicinal chemistry. 2011, Vol 18, Num 18, pp 2763-2769, 7 p ; ref : 64 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham, Oak Park, IL
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- AGC kinase PDK1 PI3K PTEN cancer metastasis
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Anticancéreux Antimétastatique Article synthèse Gène PTEN Gène suppresseur tumeur Inhibiteur enzyme Métastase Non-specific serine/threonine protein kinase Recherche et développement Thérapeutique ciblée Transduction signal Enzyme Transferases
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Antineoplastic agent Antimetastatic agent Review PTEN Gene Tumor suppressor gene Enzyme inhibitor Metastasis Non-specific serine/threonine protein kinase Research and development Targeted therapy Signal transduction Enzyme Transferases
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Anticanceroso Antimetastásico Artículo síntesis Gen PTEN Gen supresor tumor Inhibidor enzima Metástasis Non-specific serine/threonine protein kinase Investigación desarrollo Terapéutica dirigida Transducción señal Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24362916
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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