EXPOSURE OF NEURONS TO EXCITOTOXIC LEVELS OF GLUTAMATE INDUCES CLEAVAGE OF THE RNA EDITING ENZYME, ADENOSINE DEAMINASE ACTING ON RNA 2, AND LOSS OF GLUR2 EDITING
- Author
- MAHAJAN, S. S1 2 ; THAI, K. H1 ; CHEN, K1 ; ZIFF, E2
[1] School of Health Sciences, Hunter College, CUNY, New York, NY 10010, United States
[2] Department of Biochemistry, NYU School of Medicine, New York, NY 10016, United States - Source
Neuroscience. 2011, Vol 189, pp 305-315, 11 p ; ref : 1 p.3/4
- CODEN
- NRSCDN
- ISSN
- 0306-4522
- Scientific domain
- Cognition; Neurology; Physiology, morphology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- ADAR2 AMPA receptors RNA editing amyotrophic lateral sclerosis (ALS) calpain activation excitotoxicity
- Keyword (fr)
- Adenosine deaminase Calpain Enzyme Excitotoxicité Glutamate Neurone Récepteur AMPA Sclérose latérale amyotrophique Aminoacide excitateur Cysteine endopeptidases Hydrolases Maladie dégénérative Neurotransmetteur Pathologie de la moelle épinière Pathologie du système nerveux central Pathologie du système nerveux Peptidases Récepteur glutamate Toxicité
- Keyword (en)
- Adenosine deaminase Calpain Enzyme Excitotoxicity Glutamate Neuron AMPA receptor Amyotrophic lateral sclerosis Excitatory aminoacid Cysteine endopeptidases Hydrolases Degenerative disease Neurotransmitter Spinal cord disease Central nervous system disease Nervous system diseases Peptidases Glutamate receptor Toxicity
- Keyword (es)
- Adenosine deaminase Calpain Enzima Exitotoxicidad Glutamato Neurona Receptor AMPA Esclerosis lateral amiotrófica Aminoácido excitador Cysteine endopeptidases Hydrolases Enfermedad degenerativa Neurotransmisor Médula espinal patología Sistema nervosio central patología Sistema nervioso patología Peptidases Receptor glutámato Toxicidad
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24426191
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.neuroscience.2011.05.027 
https://dx.doi.org/10.1016/j.neuroscience.2011.05.027
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