Statistically significant meta-analyses of clinical trials have modest credibility and inflated effects
- Author
- PEREIRA, TiagoV1 2 ; IOANNIDIS, John P. A1 3 4
[1] Department of Hygiene and Epidemiology, Clinical Trials and Evidence-Based Medicine Unit, University of Ioannina School of Medicine, Ioannina 45110, Greece
[2] Laboratory of Genetics and Molecular Cardinlogy, Heart Institute (InCor), São Paulo, 05403-000, Brazil
[3] Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305, United States
[4] Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, United States - Source
Journal of clinical epidemiology. 2011, Vol 64, Num 10, pp 1060-1069, 10 p ; ref : 65 ref
- ISSN
- 0895-4356
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Bayes factor Bias Meta-analysis Outcomes Treatment effect Winner's curse
- Keyword (fr)
- Analyse statistique Essai clinique Médecine factuelle Métaanalyse Pronostic Traitement Biais Pratique basée sur des preuves
- Keyword (en)
- Statistical analysis Clinical trial Evidence-based medicine Metaanalysis Prognosis Treatment Evidence-based practice
- Keyword (es)
- Análisis estadístico Ensayo clínico Medicina basada en pruebas Meta-análisis Pronóstico Tratamiento Práctica basada en la evidencia
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B30 Public health. Hygiene-occupational medicine / 002B30A Public health. Hygiene / 002B30A11 Miscellaneous
- Discipline
- Public health. Hygiene-occupational medicine
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24483974
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jclinepi.2010.12.012 
https://dx.doi.org/10.1016/j.jclinepi.2010.12.012
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