ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
- Author
- ORELLANA, Juan A1 ; FROGER, Nicolas2 ; EZAN, Pascal2 ; JIANG, Jean X3 ; BENNETT, Michael V. L4 ; NAUS, Christian C5 ; GIAUME, Christian2 ; SAEZ, Juan C1 4 6
[1] Departamento de Fisiologia, Pontificia Universidad Católica de Chile, Santiago, Chile
[2] INSERM U840, Collège de France, 11 place Marcelin Berthelot, Paris, France
[3] Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States
[4] Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, United States
[5] Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, Canada
[6] Instituto Milenio, Centro Interdisciplinario de Neurociencias de Valparaíso, Valparaíso, Chile - Source
Journal of neurochemistry. 2011, Vol 118, Num 5-6, pp 826-840, 15 p ; ref : 1 p
- CODEN
- JONRA9
- ISSN
- 0022-3042
- Scientific domain
- Cell biology, histology; Neurology; Physiology, morphology
- Publisher
- Wiley-Blackwell, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Alzheimer's disease amyloid β-peptide connexin cytokines diabetes mellitus gap junctions pannexin stroke
- Keyword (fr)
- ATP Activation Astrocyte Connexine Diabète Démence d'Alzheimer Glutamate Hypoxie Inflammation Ischémie Microglie Mort cellulaire Oxygène Pathologie de l'encéphale Peptide Aminoacide excitateur Endocrinopathie Jonction cellulaire Maladie dégénérative Neurotransmetteur Névroglie Pathologie cérébrovasculaire Pathologie de l'appareil circulatoire Pathologie des vaisseaux sanguins Pathologie du système nerveux central Pathologie du système nerveux Récepteur glutamate
- Keyword (en)
- ATP Activation Astrocyte Connexin Diabetes mellitus Alzheimer disease Glutamate Hypoxia Inflammation Ischemia Microglia Cell death Oxygen Cerebral disorder Peptides Excitatory aminoacid Endocrinopathy Cell junction Degenerative disease Neurotransmitter Neuroglia Cerebrovascular disease Cardiovascular disease Vascular disease Central nervous system disease Nervous system diseases Glutamate receptor
- Keyword (es)
- ATP Activación Astrocito Connexina Diabetes Demencia Alzheimer Glutamato Hipoxia Inflamación Isquemia Microglia Muerte celular Oxígeno Encéfalo patología Péptido Aminoácido excitador Endocrinopatía Unión celular Enfermedad degenerativa Neurotransmisor Neuroglia Vaso sanguíneo encéfalo patología Aparato circulatorio patología Vaso sanguíneo patología Sistema nervosio central patología Sistema nervioso patología Receptor glutámato
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Discipline
- Endocrinopathies Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24511815
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1471-4159.2011.07210.x 
https://dx.doi.org/10.1111/j.1471-4159.2011.07210.x
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