Predicting Accelerated Aggregation Rates for Monoclonal Antibody Formulations, and Challenges for Low-Temperature Predictions
- Author
- BRUMMITT, Rebecca K1 ; NESTA, Douglas P2 ; ROBERTS, Christopher J1
[1] Department of Chemical Engineering and Center for Molecular and Engineering Thermodynamics, University of Delaware, Newark, Delaware 19716, United States
[2] Biopharmaceutical Research and Development, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, United States - Source
Journal of pharmaceutical sciences. 2011, Vol 100, Num 10, pp 4234-4243, 10 p ; ref : 32 ref
- CODEN
- JPMSAE
- ISSN
- 0022-3549
- Scientific domain
- Pharmacology drugs
- Publisher
- American Pharmaceutical Association, Washington, DC
/
Wiley, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- biotechnology kinetics protein aggregation proteins stability
- Keyword (fr)
- Agrégation Anticorps monoclonal Biotechnologie Cinétique Formulation Protéine Prédiction Stabilité Technologie pharmaceutique Température Propriété physicochimique
- Keyword (en)
- Aggregation Monoclonal antibody Biotechnology Kinetics Formulation Protein Prediction Stability Pharmaceutical technology Temperature Physicochemical properties
- Keyword (es)
- Agregación Anticuerpo monoclonal Biotecnología Cinética Formulación Proteína Predicción Estabilidad Tecnología farmacéutica Temperatura Propiedad fisicoquímica
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24566792
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jps.22633 
https://dx.doi.org/10.1002/jps.22633
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