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Predicting solution aggregation rates for therapeutic proteins: Approaches and challenges

Author
ROBERTS, Christopher J1 ; DAS, Tapan K2 ; SAHIN, Erinc1
[1] Department of Chemical Engineering and Center for Molecular and Engineering Thermodynamics, University of Delaware, Newark, DE 19716, United States
[2] Biotherapeutics Research and Development, Pfizer, Inc., Chesterfield, MO 63017, United States
Issue title
A priori Performance Predictions
Author (monograph)
HANCOCK, Bruno C (Editor)1 ; MORRIS, Kenneth R (Editor)2 ; WILDFONG, Peter L. D (Editor)3
[1] Pfizer Inc., Groton, CT, United States
[2] University of Hawaii-Hilo, Hilo, HI, United States
[3] Duquesne University, Pittsburgh, PA, United States
Source

International journal of pharmaceutics (Print). 2011, Vol 418, Num 2, pp 318-333, 16 p ; ref : 1 p.3/4

CODEN
IJPHDE
ISSN
0378-5173
Scientific domain
Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Biotechnology Modeling Non-native aggregation Protein stability
Keyword (fr)
Agrégation Biotechnologie Modélisation Protéine Prédiction Solution Stabilité Technologie pharmaceutique Traitement Propriété physicochimique
Keyword (en)
Aggregation Biotechnology Modeling Protein Prediction Solution Stability Pharmaceutical technology Treatment Physicochemical properties
Keyword (es)
Agregación Biotecnología Modelización Proteína Predicción Solución Estabilidad Tecnología farmacéutica Tratamiento Propiedad fisicoquímica
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24637020

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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