Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins
- Author
- XU, Yongmei1 ; MASUKO, Sayaka2 ; TAKIEDDIN, Majde3 ; XU, Haoming1 ; LIU, Renpeng1 ; JING, Juliana1 ; MOUSA, Shaker A3 4 ; LINHARDT, Robert J2 ; LIU, Jan1
[1] Division of Medicinal Chemistry and Natural Products, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, United States
[2] Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, United States
[3] Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY 12208, United States
[4] College of Medidne, King Saud University, Riyadh, Saudi Arabia - Source
Science (Washington, D.C.). 2011, Vol 334, Num 6055, pp 498-501, 4 p ; ref : 34 ref
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Animal Anticoagulant Fondaparinux sodique Homogénéité Héparine bas poids moléculaire In vitro Pharmacocinétique Souris Synthèse chimique Synthèse enzymatique Héparine d'ultra bas poids moléculaire Inhibiteur enzyme Mammalia Pentaoside Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Anticoagulant Fondaparinux sodium Homogeneity Low molecular weight heparin In vitro Pharmacokinetics Mouse Chemical synthesis Enzymatic synthesis Enzyme inhibitor Mammalia Pentasaccharide Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Anticoagulante Fondaparinux de sodio Homogeneidad Heparina bajo peso molecular In vitro Farmacocinética Ratón Síntesis química Síntesis enzimática Inhibidor enzima Mammalia Pentaholósido Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02G Blood. Blood coagulation. Reticuloendothelial system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24707683
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1207478 
https://dx.doi.org/10.1126/science.1207478
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