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A Novel Kinase Inhibitor, INCB28060, Blocks c-MET-Dependent Signaling, Neoplastic Activities, and Cross-Talk with EGFR and HER-3

Author
XIANGDONG LIU1 ; QIAN WANG1 ; BOER, Jason1 ; DIAMOND, Sharon1 ; CHUNHONG HE1 ; MEIZHONG XU1 ; JINCONG ZHUO1 ; WENQING YAO1 ; NEWTON, Robert C1 ; SCHERLE, Peggy A1 ; GENGJIE YANG1 ; MARANDO, Cindy1 ; KOBLISH, Holly K1 ; HALL, Leslie M1 ; FRIDMAN, Jordan S1 ; BEHSHAD, Elham1 ; WYNN, Richard1 ; YU LI1
[1] Incyte Corporation, Wilmington, Delaware, United States
Source

Clinical cancer research (Print). 2011, Vol 17, Num 22, pp 7127-7138, 12 p ; ref : 36 ref

CODEN
CCREF4
ISSN
1078-0432
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
American Association for Cancer Research, Philadelphia, PA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Gène onc cellulaire Inhibiteur Kinase Protooncogène Récepteur facteur croissance épiderme Transduction signal Tumeur maligne Gène met Récepteur HER3 Cancer Enzyme Transferases
Keyword (en)
Biological activity C-Onc gene Inhibitor Kinase Protooncogene Epidermal growth factor receptor Signal transduction Malignant tumor Human Epidermal growth factor Receptor 3 Cancer Enzyme Transferases
Keyword (es)
Actividad biológica Gen onc celular Inhibidor Kinase Protooncogen Receptor del factor de crecimiento epidérmico Transducción señal Tumor maligno Cáncer Enzima Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
25229376

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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