Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
- Author
- GOTINK, Kristy J1 ; BROXTERMAN, Henk J1 ; GRIFFIOEN, Arjan W1 ; ASSARAF, Yehuda G1 6 ; PILI, Roberto7 ; PETERS, Godefridus J1 ; VERHEUL, Henk M. W1 ; LABOTS, Mariette1 ; DE HAAS, Richard R1 ; DEKKER, Henk1 ; HONEYWELL, Richard J1 ; RUDEK, Michelle A5 ; BEEREPOOT, Laurens V4 ; MUSTERS, René J2 ; JANSEN, Gerrit3
[1] Department of Medical Oncoloqy, VU University Medical Center, Amsterdam, Netherlands Antilles
[2] Department of Physioloqy, VU University Medical Center, Amsterdam, Netherlands Antilles
[3] Department of Rheumatology, VU University Medical Center, Amsterdam, Netherlands Antilles
[4] Department of Internal Medicine, St. Elisabeth Hospital, Tilburg, Netherlands
[5] The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States
[6] The Fred Wyszkowski Cancer Research Laboratory, Department of Biology, Technion-Israel Institute of Technology, Haifa, Israel
[7] Genitourinary Program, Roswell Park Cancer Institute, Buffalo, New York, United States - Source
Clinical cancer research (Print). 2011, Vol 17, Num 23, pp 7337-7346, 10 p ; ref : 34 ref
- CODEN
- CCREF4
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiangiogénique Anticancéreux Lysosome Mécanisme action Résistance traitement Sunitinib Enzyme Inhibiteur de la tyrosine kinase Inhibiteur enzyme Inhibiteur multikinase Protein-tyrosine kinase Transferases
- Keyword (en)
- Antiangiogenic agent Antineoplastic agent Lysosome Mechanism of action Treatment resistance Sunitinib Enzyme Tyrosine kinase inhibitor Enzyme inhibitor Multikinase inhibitor Protein-tyrosine kinase Transferases
- Keyword (es)
- Antiangiogenico Anticanceroso Lisosoma Mecanismo acción Resistencia tratamiento Sunitinib Enzima Inhibidor tyrosine kinase Inhibidor enzima inhibidor multicinasa Protein-tyrosine kinase Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25254501
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-11-1667 
https://dx.doi.org/10.1158/1078-0432.CCR-11-1667
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