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A Novel and Enantioselective Total Synthesis of (20S)-Camptothecin via a Sharpless Asymmetric Dihydroxylation Strategy

Author
LEI ZHAO1 2 ; XIONG, Fang-Jun1 ; CHEN, Wen-Xue1 ; CHEN, Fen-Er1 2
[1] Fudan-DSM Joint Lab for Synthetic Method and Chiral Technology, Department of Chemistry, Fudan University, Shanghai, 200433, China
[2] Institutes of Biomedical Sciences, Fudan University, Shanghai, 200031, China
Source

Synthesis (Stuttgart). 2011, Num 24, pp 4045-4049, 5 p ; ref : 11 ref

CODEN
SYNTBF
ISSN
0039-7881
Scientific domain
Organic chemistry
Publisher
Thieme, Stuttgart
Publication country
Germany
Document type
Article
Language
English
Author keyword
Heck reaction antitumor agents asymmetric catalysis stereoselectivity total synthesis
Keyword (fr)
Anticancéreux Camptothécine Catalyse asymétrique Dérivé de l'acide nicotinique Dérivé de la pyridine Enantiosélectivité Hétérocycle azote Réaction Heck Stéréosélectivité Synthèse asymétrique Synthèse totale Dihydroxylation de Sharpless
Keyword (en)
Antineoplastic agent Asymmetric catalysis Nicotinic acid derivatives Pyridine derivatives Enantioselectivity Nitrogen heterocycle Heck reaction Stereoselectivity Asymmetric synthesis Total synthesis Sharpless dihydroxylation
Keyword (es)
Anticanceroso Catálisis asimétrica Piridina derivado Enantioselectividad Heterociclo nitrógeno Reacción Heck Estereoselectividad Síntesis asimétrica Síntesis total
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06B Heterocyclic compounds with only one n hetero atom and condensed derivatives

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Organic chemistry Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
25273741

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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