Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings
- Author
- O'BRIEN, Fionn E1 2 ; DINAN, Timothy G1 3 ; GRIFFIN, Brendan T2 ; CRYAN, John F1 2 4
[1] Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
[2] School of Pharmacy, University College Cork, Cork, Ireland
[3] Department of Psychiatry University College Cork, Cork, Ireland
[4] Department of Anatomy, University College Cork, Cork, Ireland - Source
British journal of pharmacology. 2012, Vol 165, Num 2, pp 289-312, 24 p ; ref : 5 p.1/4
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- ABC drug efflux transporter ABCB1 MDR1 P-glycoprotein antidepressant blood-brain barrier treatment-resistant depression
- Keyword (fr)
- Antidépresseur Barrière hématoencéphalique Etat dépressif Glycoprotéine P Gène MDR1 In vitro In vivo Interaction Médicament Psychotrope Transport membranaire Transporteur ABC Encéphale Pharmacocinétique Système nerveux central Trouble de l'humeur
- Keyword (en)
- Antidepressant agent Blood brain barrier Depression P Glycoprotein MDR-1 gene In vitro In vivo Interaction Drug Psychotropic Membrane transport ABC transporter Encephalon Pharmacokinetics Central nervous system Mood disorder
- Keyword (es)
- Antidepresor Barrera hematoencefálica Estado depresivo Glicoproteína P Gen MDR-1 In vitro In vivo Interacción Medicamento Psicotropo Transporte membranal Transportador ABC Encéfalo Farmacocinética Sistema nervioso central Trastorno humor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C07 Mood disorders / 002B18C07A Depression
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03G Mood disorders / 770-D03G01 Depression
- Discipline
- General pharmacology Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 25344336
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1476-5381.2011.01557.x 
https://dx.doi.org/10.1111/j.1476-5381.2011.01557.x
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