Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2β construct allows the study of topoisomerase IIβ inhibitors in yeast
- Author
- MECZES, E. L1 ; MARSH, K. L1 ; FISHER, L. M2 ; PERENNA ROGERS, M1 ; AUSTIN, C. A1
[1] Department of Biochemistry and Genetics, The Medical School, The University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, NE2 4HH, United Kingdom
[2] Molecular Genetics Group, Department of Cellular and Molecular Sciences, St. George's Hospital Medical School, London SW17 ORE, United Kingdom - Source
Cancer chemotherapy and pharmacology. 1997, Vol 39, Num 4, pp 367-375 ; ref : 36 ref
- CODEN
- CCPHDZ
- ISSN
- 0344-5704
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Complémentation DNA topoisomerase (ATP-hydrolysing) Homme In vitro Inhibiteur enzyme Isozyme Mutation thermosensible Mécanisme Méthode étude Résistance Saccharomyces cerevisiae Test activité DNA topoisomerase (ATP-hydrolysing) β DNA topoisomerase IIβ Ascomycetes Enzyme Fungi Isomerases Thallophyta
- Keyword (en)
- Antineoplastic agent Complementation DNA topoisomerase (ATP-hydrolysing) Human In vitro Enzyme inhibitor Isozyme Temperature sensitive mutation Mechanism Investigation method Resistance Saccharomyces cerevisiae Screening test Ascomycetes Enzyme Fungi Isomerases Thallophyta
- Keyword (es)
- Anticanceroso Complementación DNA topoisomerase (ATP-hydrolysing) Hombre In vitro Inhibidor enzima Isozima Mutación termosensible Mecanismo Método estudio Resistencia Saccharomyces cerevisiae Prueba actividad Ascomycetes Enzima Fungi Isomerases Thallophyta
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2537631
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s002800050585 
https://dx.doi.org/10.1007/s002800050585
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