Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway
- Author
- SUN, Ji-Min1 2 ; KIM, Seong-Jun1 ; OH, Jong-Won1 2 ; KIM, Geon-Woo1 2 ; RHEE, Jin-Kyu1 ; KIM, Nam Doo3 ; JUNG, Heeyong1 ; JEUN, Jungae1 ; LEE, Seung-Hoon1 2 ; SEUNG HYUN HAN4 ; CHUL SOO SHIN1
[1] Department of Biotechnology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Korea, Republic of
[2] Center for Protein Function Control, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Korea, Republic of
[3] New Drug Development Center, Doegu-Gyeongbuk Medical Innovation Foundation, Daegu 706-010, Korea, Republic of
[4] Department of Oral Microbiology and Immunology, Dental Research Institute, School of Dentistry, Seoul National University, Seoul 110-749, Korea, Republic of - Source
Journal of antimicrobial chemotherapy (Print). 2012, Vol 67, Num 1, pp 49-58, 10 p ; ref : 43 ref
- CODEN
- JACHDX
- ISSN
- 0305-7453
- Scientific domain
- Microbiology, infectious diseases; Pharmacology drugs
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- HCV HMG-CoA reductase RNA-dependent RNA polymerase
- Keyword (fr)
- Activité biologique Biosynthèse DNA-directed RNA polymerase Hydroxymethylglutaryl-CoA reductase Hépatite virale C Inhibiteur Inhibition Monascus Pigment RNA-directed RNA polymerase Réplication Virus hépatite C Ascomycota Enzyme Flaviviridae Fungi Hepacivirus Infection Nucleotidyltransferases Oxidoreductases Pathologie de l'appareil digestif Pathologie du foie Transferases Virose Virus
- Keyword (en)
- Biological activity Biosynthesis DNA-directed RNA polymerase Hydroxymethylglutaryl-CoA reductase Viral hepatitis C Inhibitor Inhibition Monascus Pigments RNA-directed RNA polymerase Replication Hepatitis C virus Ascomycota Enzyme Flaviviridae Fungi Hepacivirus Infection Nucleotidyltransferases Oxidoreductases Digestive diseases Hepatic disease Transferases Viral disease Virus
- Keyword (es)
- Actividad biológica Biosíntesis DNA-directed RNA polymerase Hydroxymethylglutaryl-CoA reductase Hepatítis virica C Inhibidor Inhibición Monascus Pigmento RNA-directed RNA polymerase Replicación Hepatitis C virus Ascomycota Enzima Flaviviridae Fungi Hepacivirus Infección Nucleotidyltransferases Oxidoreductases Aparato digestivo patología Hígado patología Transferases Virosis Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02G Viral hepatitis
- Discipline
- Infectious pathology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25572786
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/jac/dkr432 
https://dx.doi.org/10.1093/jac/dkr432
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