Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone : Effects of dose and phenethyl isothiocyanate
- Author
- STARETZ, M. E1 ; FOILES, P. G1 ; MIGLIETTA, L. M1 ; HECHT, S. S1
[1] American Health Foundation, Valhalla, New York 10595, United States - Source
Cancer research (Baltimore). 1997, Vol 57, Num 2, pp 259-266 ; ref : 40 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activation métabolique Adduit moléculaire Alkylation Animal Anticarcinogène Bronchopulmonaire Butan-1-one(4-[méthyl nitroso amino]-1-[3-pyridyl]) Carcinogenèse Carcinogène DNA Mécanisme action Nicotine Nitrosamine Rat Tabac Tabagisme Toxicité Tumeur maligne Voie orale Isothiocyanique acide(phenethyl) NNK Appareil respiratoire pathologie Bronche pathologie Mammalia Poumon pathologie Rodentia Vertebrata
- Keyword (en)
- Metabolic activation Molecular adduct Alkylation Animal Anticarcinogen Bronchopulmonary Carcinogenesis Carcinogen DNA Mechanism of action Nicotine Nitrosamine Rat Tobacco Tobacco smoking Toxicity Malignant tumor Oral administration Respiratory disease Bronchus disease Mammalia Lung disease Rodentia Vertebrata
- Keyword (es)
- Activación metabólica Producto adición molecular Alquilación Animal Anticarcinógeno Broncopulmonar Carcinogénesis Carcinógeno DNA Mecanismo acción Nicotina Nitrosamina Rata Tabaco Tabaquismo Toxicidad Tumor maligno Vía oral Aparato respiratorio patología Bronquio patología Mammalia Pulmón patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03E Tobacco, tobacco smoking
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2559168
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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