A naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblasts
- Author
- SWARNKAR, Gaurav1 ; SHARAN, Kunal1 ; SANYAL, Sabyasachi2 ; CHATTOPADHYAY, Naibedya1 ; SIDDIQUI, Jawed A1 ; SHARAN MISHRA, Jay2 ; KHAN, Kainat2 ; PARVEZ KHAN, Mohd1 ; GUPTA, Varsha3 ; RAWAT, Preeti4 ; MAURYA, Rakesh4 ; DWIVEDI, Anil K3
[1] Division of Endocrinology, CSIR-Central Drug Research Institute, Chattar Manzil, Lucknow, India
[2] Division of Drug Target Discovery and Development, CSIR-Central Drug Research Institute, Chattar Manzil, Lucknow, India
[3] Pharmacokinetics Division, CSIR-Central Drug Research Institute, Chattar Manzil, Lucknow, India
[4] Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Chattar Manzil, Lucknow, India - Source
British journal of pharmacology. 2012, Vol 165, Num 5, pp 1526-1542, 17 p ; ref : 2 p
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- bioavailability bone marrow bone microarchitecture flavanones mineralization oestrogen deficiency osteoblast differentiation osteoporosis parathyroid hormone preclinical development
- Keyword (fr)
- Anabolisant Biodisponibilité Différenciation Déficit Développement Essai préclinique Hormone parathyroïde Hormone stéroïde sexuelle Minéralisation Moelle osseuse Oestrogène Os Ostéoblaste Ostéoporose Pharmacocinétique Flavanone Naringénine dérivé Dérivé de la flavanone Flavonoïde Hormone ovarienne Hormone peptide Pathologie du système ostéoarticulaire Phénols Polyphénol Système ostéoarticulaire
- Keyword (en)
- Anabolic agent Bioavailability Differentiation Deficiency Development Preclinical trial Parathyroid hormone Sex steroid hormone Mineralization Bone marrow Estrogen Bone Osteoblast Osteoporosis Pharmacokinetics Flavanone derivatives Flavonoid Ovarian hormone Peptide hormone Diseases of the osteoarticular system Phenols Polyphenol Osteoarticular system
- Keyword (es)
- Agente anabólico Biodisponibilidad Diferenciación Déficiencia Desarrollo Ensayo preclínico Hormona paratiroidea Hormona esteroide sexual Mineralización Médula ósea Estrógeno Hueso Osteoblasto Osteoporosis Farmacocinética Flavanona derivado Flavonoide Hormona ovárica Hormona péptido Sistema osteoarticular patología Fenoles Polifenol Sistema osteoarticular
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15A Osteoporosis. Osteomalacia. Paget disease
- Discipline
- General pharmacology Osteoarticular pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25614793
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1476-5381.2011.01637.x 
https://dx.doi.org/10.1111/j.1476-5381.2011.01637.x
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