Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia
- Author
- LORYAN, Irena1 ; LINDQVIST, Marja1 ; JOHANSSON, Inger1 ; HIRATSUKA, Masahiro1 ; DER HEIDEN, Ilse Van2 ; SCHAIK, Ron Hn Van2 ; JAKOBSSON, Jan1 ; INGELMAN-SUNDBERG, Magnus1
[1] Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
[2] Department of Clinical Chemistry, Erasmus MC Rotterdam, Rotterdam, Netherlands - Source
European journal of clinical pharmacology. 2012, Vol 68, Num 4, pp 397-406, 10 p ; ref : 40 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Anesthesia CYP2B6 Metabolism Propofol Sex UGT1A9
- Keyword (fr)
- Anesthésie Anesthésique général Cytochrome P450 Homme Isozyme Médicament Métabolisme Pharmacothérapie Propofol Sexe UDP-glucuronosyltransferase Cytochrome P450 2B6 Enzyme Glycosyltransferases Hexosyltransferases Pharmacocinétique Traitement Transferases
- Keyword (en)
- Anesthesia General anesthetic Cytochrome P450 Human Isozyme Drug Metabolism Pharmacotherapy Propofol Sex UDP-glucuronosyltransferase Cytochrome P450 2B6 Enzyme Glycosyltransferases Hexosyltransferases Pharmacokinetics Treatment Transferases
- Keyword (es)
- Anestesia Anestésico general Citocromo P450 Hombre Isozima Medicamento Metabolismo Farmacoterapia Propofol Sexo UDP-glucuronosyltransferase Cytochrome P450 2B6 Enzima Glycosyltransferases Hexosyltransferases Farmacocinética Tratamiento Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25648277
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1007/s00228-011-1132-2 
https://dx.doi.org/10.1007/s00228-011-1132-2
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-011-1132-2\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2012\";s:9:\"\u0000*\u0000volume\";s:2:\"68\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"397\";s:8:\"\u0000*\u0000epage\";s:3:\"406\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"LORYAN\";s:10:\"\u0000*\u0000aufirst\";s:5:\"Irena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:16:\"LINDQVIST, Marja\";i:1;s:16:\"JOHANSSON, Inger\";i:2;s:19:\"HIRATSUKA, Masahiro\";i:3;s:20:\"DER HEIDEN, Ilse Van\";i:4;s:18:\"SCHAIK, Ron Hn Van\";i:5;s:14:\"JAKOBSSON, Jan\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-011-1132-2\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2012\";s:9:\"\u0000*\u0000volume\";s:2:\"68\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"397\";s:8:\"\u0000*\u0000epage\";s:3:\"406\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"LORYAN\";s:10:\"\u0000*\u0000aufirst\";s:5:\"Irena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:16:\"LINDQVIST, Marja\";i:1;s:16:\"JOHANSSON, Inger\";i:2;s:19:\"HIRATSUKA, Masahiro\";i:3;s:20:\"DER HEIDEN, Ilse Van\";i:4;s:18:\"SCHAIK, Ron Hn Van\";i:5;s:14:\"JAKOBSSON, Jan\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-011-1132-2\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-011-1132-2\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2012\";s:9:\"\u0000*\u0000volume\";s:2:\"68\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"397\";s:8:\"\u0000*\u0000epage\";s:3:\"406\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"LORYAN\";s:10:\"\u0000*\u0000aufirst\";s:5:\"Irena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:16:\"LINDQVIST, Marja\";i:1;s:16:\"JOHANSSON, Inger\";i:2;s:19:\"HIRATSUKA, Masahiro\";i:3;s:20:\"DER HEIDEN, Ilse Van\";i:4;s:18:\"SCHAIK, Ron Hn Van\";i:5;s:14:\"JAKOBSSON, Jan\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-011-1132-2\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2012\";s:9:\"\u0000*\u0000volume\";s:2:\"68\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"397\";s:8:\"\u0000*\u0000epage\";s:3:\"406\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"LORYAN\";s:10:\"\u0000*\u0000aufirst\";s:5:\"Irena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:16:\"LINDQVIST, Marja\";i:1;s:16:\"JOHANSSON, Inger\";i:2;s:19:\"HIRATSUKA, Masahiro\";i:3;s:20:\"DER HEIDEN, Ilse Van\";i:4;s:18:\"SCHAIK, Ron Hn Van\";i:5;s:14:\"JAKOBSSON, Jan\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-011-1132-2\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2012\";s:9:\"\u0000*\u0000volume\";s:2:\"68\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"397\";s:8:\"\u0000*\u0000epage\";s:3:\"406\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"LORYAN\";s:10:\"\u0000*\u0000aufirst\";s:5:\"Irena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:16:\"LINDQVIST, Marja\";i:1;s:16:\"JOHANSSON, Inger\";i:2;s:19:\"HIRATSUKA, Masahiro\";i:3;s:20:\"DER HEIDEN, Ilse Van\";i:4;s:18:\"SCHAIK, Ron Hn Van\";i:5;s:14:\"JAKOBSSON, Jan\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
