Clarifying the Spectrum of Driver Oncogene Mutations in Biomarker-Verified Squamous Carcinoma of Lung: Lack of EGFR/KRAS and Presence of PIK3CA/AKT1 Mutations
- Author
- REKHTMAN, Natasha1 ; PAIK, Paul K2 ; ARCILA, Maria E1 ; TAFE, Laura J1 ; OXNARD, Geoffrey R2 ; MOREIRA, Andre L1 ; TRAVIS, William D1 ; ZAKOWSKI, Maureen F1 ; KRIS, Mark G2 ; LADANYI, Marc1 3
[1] Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States
[2] Thoracic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, United States
[3] Department of Medicine, and Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, United States - Source
Clinical cancer research (Print). 2012, Vol 18, Num 4, pp 1167-1176, 10 p ; ref : 50 ref
- CODEN
- CCREF4
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Bronchopulmonaire Cancer du poumon Carcinome bronchopulmonaire Carcinome épidermoïde Gène K ras Gène onc cellulaire Gène onc Génétique Marqueur biologique Mutation Protooncogène Récepteur facteur croissance épiderme Spectre Cancer Enzyme Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Transferases Tumeur maligne
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Bronchopulmonary Lung cancer Bronchopulmonary carcinoma Squamous cell carcinoma K ras Gene C-Onc gene Onc gene Genetics Biological marker Mutation Protooncogene Epidermal growth factor receptor Spectrum Cancer Enzyme Respiratory disease Bronchus disease Lung disease Transferases Malignant tumor
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Broncopulmonar Cáncer del pulmón Carcinoma bronchopulmonar Carcinoma epidermoide Gen K ras Gen onc celular Gen onc Genética Marcador biológico Mutación Protooncogen Receptor del factor de crecimiento epidérmico Espectro Cáncer Enzima Aparato respiratorio patología Bronquio patología Pulmón patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pharmacological treatments Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25698121
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-11-2109 
https://dx.doi.org/10.1158/1078-0432.CCR-11-2109
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