Targeting of Multidrug-Resistant Human Ovarian Carcinoma Cells With Anti-P-Glycoprotein Antibody Conjugates
- Author
- FOWERS, Kirk D1 ; KOPECEK, Jindřich1 2
[1] Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, United States
[2] Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112, United States - Source
Macromolecular bioscience (Print). 2012, Vol 12, Num 4, pp 502-514, 13 p ; ref : 80 ref
- ISSN
- 1616-5187
- Scientific domain
- Biotechnology; Polymers, paint and wood industries
- Publisher
- Wiley-VCH, Weinheim
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Alcool copolymère Anticancéreux Anticorps monoclonal Cancer de l'ovaire Capacité fixation Cellule tumorale Ciblage Copolymérisation radicalaire Copulation chimique Doxorubicine Etude expérimentale Glycoprotéine P Groupe latéral In vitro Internalisation Modification chimique Méthacrylamide dérivé copolymère Photosensibilisant Photothérapie dynamique Polymère vecteur Promédicament Préparation Relation concentration activité Résistance multiple Transport intracellulaire Vecteur médicament Conjugué polymère anticorps monoclonal Lignée A2780 Méthacrylamide(N-[2-hydroxypropyl]) copolymère
- Keyword (en)
- Biological activity Alcohol copolymer Antineoplastic agent Monoclonal antibody Ovary cancer Binding capacity Tumor cell Targeting Radical copolymerization Chemical coupling Doxorubicin Experimental study P Glycoprotein Lateral group In vitro Internalization Chemical modification Methacrylamide derivative copolymer Photosensitizer Photodynamic therapy Control release polymer Prodrug Preparation Activity concentration relation Multiple resistance Intracellular transport Drug carrier
- Keyword (es)
- Actividad biológica Alcohol copolímero Anticanceroso Anticuerpo monoclonal Cáncer del ovario Capacidad de fijación Célula tumoral Blancado Copolimerización radical Copulación química Doxorubicina Estudio experimental Glicoproteína P Grupo lateral In vitro Internalización Modificación química Metacrilamida derivado copolímero Fotosensibilizante Fototerapia dinamica Polímero vector Promedicamento Preparación Relación concentración actividad Resistencia múltiple Transporte intracelular Vector medicamento
- Classification
- Pascal
- 001 Exact sciences and technology / 001D Applied sciences / 001D09 Physicochemistry of polymers / 001D09D Organic polymers / 001D09D03 Chemical reactions and properties / 001D09D03A Chemical modifications
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments Physical chemistry of polymers
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25835646
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/mabi.201100350 
https://dx.doi.org/10.1002/mabi.201100350
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