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A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits

Author
BHATTACHARJEE, Samsiddhi1 ; RAJARAMAN, Preetha2 ; CHATTERJEE, Nilanjan1 ; JACOBS, Kevin B3 ; WHEELER, William A4 ; MELIN, Beatrice S5 ; HARTGE, Patricia6 ; CONSORTIUM, Gliomascan7 ; YEAGER, Meredith3 ; CHUNG, Charles C8 ; CHANOCK, Stephen J8
[1] Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, Maryland 20852, United States
[2] Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, Maryland 20852, United States
[3] Core Genotyping Facility, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 8717 Grovemont Circle, Gaithersburg, Maryland 20877, United States
[4] Information Management Services, Rockville, MD 20852, United States
[5] Department of Radiation Sciences, Oncology, Umea University, 90187 Umeå, Sweden
[6] Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, United States
[7] GliomaScan Consortium investigators and affiliations are available in the Supplemental Data, United States
[8] Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, United States
Source

American journal of human genetics. 2012, Vol 90, Num 5, pp 821-835, 15 p ; ref : 36 ref

CODEN
AJHGAG
ISSN
0002-9297
Scientific domain
Genetics
Publisher
Cell Press, Cambridge, MA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Déterminisme génétique Génétique Homme Interprétation Puissance Association génétique Linkage
Keyword (en)
Genetic determinism Genetics Human Interpretation Power
Keyword (es)
Determinismo genético Genética Hombre Interpretación Potencia
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B23 Medical genetics / 002B23A General aspects. Genetic counseling

Discipline
Eukaryotes genetics. Biological and molecular evolution Medical genetics Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
25863106

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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