A Phase 1 Dose-Escalation Study of ARRY-520, a Kinesin Spindle Protein Inhibitor, in Patients With Advanced Myeloid Leukemias
- Author
- JEAN KHOURY, Hanna1 ; GARCIA-MANERO, Guillermo2 ; KARAN, Sharon3 ; SIMMONS, Heidi3 ; MARCUS, Adam I1 ; PTASZYNSKI, Mieke3 ; KANTARJIAN, Hagop2 ; BORTHAKUR, Gautam2 ; KADIA, Tapan2 ; CIELO FOUDRAY, Maria2 ; ARELLANO, Martha1 ; LANGSTON, Amelia1 ; BETHELMIE-BRYAN, Beverly1 ; RUSH, Selena3 ; LITWILER, Kevin3
[1] Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, United States
[2] Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas, United States
[3] Array BioPharma, Boulder, Colorado, United States - Source
Cancer. 2012, Vol 118, Num 14, pp 3556-3564, 9 p ; ref : 36 ref
- CODEN
- CANCAR
- ISSN
- 0008-543X
- Scientific domain
- Medical oncology
- Publisher
- Wiley-Blackwell, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- ARRY-520 advanced myeloid leukemia kinesin spindle protein inhibitor maximum tolerated dose myelodysplastic syndrome phase 1 relapsed
- Keyword (fr)
- Cancérologie Dose croissante Essai clinique phase I Homme Inhibiteur protéique Leucémie myéloïde chronique Protéine A Récidive Stade avancé Syndrome myélodysplasique Cancer Hémopathie maligne Syndrome myéloprolifératif
- Keyword (en)
- Cancerology Increasing dose Phase I trial Human Protein inhibitor Chronic myelogenous leukemia Protein A Relapse Advanced stage Myelodysplastic syndrome Cancer Malignant hemopathy Myeloproliferative syndrome
- Keyword (es)
- Cancerología Dosis creciente Ensayo clínico fase I Hombre Inhibidor proteico Leucemia mieloidea crónica Proteína A Recaida Estadio avanzado Mielodisplastico síndrome Cáncer Hemopatía maligna Mieloproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26098549
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/cncr.26664 
https://dx.doi.org/10.1002/cncr.26664
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