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A Single-Nucleotide Polymorphism in the Methylene Tetrahydrofolate Reductase (MTHFR) Gene Is Associated With Risk of Radiation Pneumonitis in Lung Cancer Patients Treated With Thoracic Radiation Therapy

Author
MAK, Raymond H1 ; ALEXANDER, Brian M2 ; WILLERS, Henning6 ; CHOI, Noah C6 ; CHRISTIANI, David C3 ; ASOMANING, Kofi3 ; HEIST, Rebecca S3 4 ; LIU, Chen-Yu3 5 ; LI SU3 ; RIHONG ZHAI3 ; ANCUKIEWICZ, Marek6 ; NAPOLITANO, Brian6 ; NIEMIERKO, Andrzej6
[1] Harvard Radiation Oncology Program, Boston, Massachusetts, United States
[2] Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Massachusetts, United States
[3] Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States
[4] Division of Hematology/Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States
[5] Institute of Environmental Health, National Taiwan University, Taipei, Taiwan, Province of China
[6] Department of Radiation Oncology, Massachusetts General Hospital Boston, Massachusetts, United States
Source

Cancer. 2012, Vol 118, Num 14, pp 3654-3665, 12 p ; ref : 21 ref

CODEN
CANCAR
ISSN
0008-543X
Scientific domain
Medical oncology
Publisher
Wiley-Blackwell, Hoboken, NJ
Publication country
United States
Document type
Article
Language
English
Author keyword
MTHFR lung cancer oxidative stress radiation pneumonitis single-nucleotide polymorphism
Keyword (fr)
Cancer du poumon Cancérologie Facteur risque Gène Génotype Génétique Homme Methylenetetrahydrofolate reductase (NADPH) Pneumonie Polymorphisme mononucléotide Radiothérapie Stress oxydatif Traitement Variabilité génétique Cancer Enzyme Oxidoreductases Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Tumeur maligne
Keyword (en)
Lung cancer Cancerology Risk factor Gene Genotype Genetics Human Methylenetetrahydrofolate reductase (NADPH) Pneumonia Single nucleotide polymorphism Radiotherapy Oxidative stress Treatment Genetic variability Cancer Enzyme Oxidoreductases Respiratory disease Bronchus disease Lung disease Malignant tumor
Keyword (es)
Cáncer del pulmón Cancerología Factor riesgo Gen Genotipo Genética Hombre Methylenetetrahydrofolate reductase (NADPH) Neumonía Polimorfismo mononucleótido Radioterapia Estrés oxidativo Tratamiento Variabilidad genética Cáncer Enzima Oxidoreductases Aparato respiratorio patología Bronquio patología Pulmón patología Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum

Discipline
Pulmonology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
26098561

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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