Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT
- Author
- NEGRO, Roberto1 ; GOBESSI, Stefania1 ; LONGO, Pablo G1 ; HE, Yantao2 ; ZHANG, Zhong-Yin2 ; LAURENTI, Luca3 ; EFREMOV, Dimitar G1
[1] Molecular Hematology, International Centre for Genetic Engineering & Biotechnology, CampusA. Buzzati-Traverso, Rome, Italy
[2] Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, Italy
[3] Department of Hematology, Catholic University Hospital A. Gemelli, Rome, Italy - Source
Blood. 2012, Vol 119, Num 26, pp 6278-6287, 10 p ; ref : 50 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Akt protein kinase Antigène Autoimmunité Hématologie Leucémie lymphoïde chronique Phosphoric monoester hydrolases Surexpression génique Survie Cancer Enzyme Esterases Hydrolases Hémopathie maligne Syndrome lymphoprolifératif
- Keyword (en)
- Akt protein kinase Antigen Autoimmunity Hematology Chronic lymphocytic leukemia Phosphoric monoester hydrolases Gene overexpression Survival Cancer Enzyme Esterases Hydrolases Malignant hemopathy Lymphoproliferative syndrome
- Keyword (es)
- Akt protein kinase Antígeno Autoinmunidad Hematología Leucemia linfoidea crónica Phosphoric monoester hydrolases Sobreexpresión genética Sobrevivencia Cáncer Enzima Esterases Hydrolases Hemopatía maligna Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26112993
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2012-01-403162 
https://dx.doi.org/10.1182/blood-2012-01-403162
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