Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice, With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia
- Author
- KANTARJIAN, Hagop M1 ; THOMAS, Xavier G2 ; KUO, Ching-Yuan12 ; ORIOL, Albert14 ; RAVANDI, Farhad1 ; FADERL, Stefan1 ; DELAUNAY, Jacques15 16 ; LYSAK, Daniel8 ; MINDEN, Mark; ARTHUR, Christopher; DMOSZYNSKA, Anna3 ; WIERZBOWSKA, Agnieszka4 ; MAZUR, Grzegorz5 ; MAYER, Jiri6 7 ; GAU, Jyh-Pyng10 ; CHOU, Wen-Chien11 ; BUCKSTEIN, Rena13 ; CERMAK, Jaroslav9
[1] University of Texas MD Anderson Cancer Center, Houston, TX, United States
[2] Hôpital Edouard Herriot, Lyon, France
[3] Medical University of Lublin, Lublin, Poland
[4] Medical University of Lodz, Lodz, Poland
[5] Wroclaw Medical University, Wroclaw, Poland
[6] University Hospital Brno, Czech Republic
[7] Central European Institute of Technology, Masaryk University, Brno, Czech Republic
[8] University Hospital Plzeň, Plzeň, Czech Republic
[9] Charles University, Prague, Czech Republic
[10] Taipei Veterans General Hospital, Taiwan, Province of China
[11] National Taiwan University Hospital, Taipei, Taiwan, Province of China
[12] Chang Gung University College of Medicine, Kaohsiung, Taiwan, Province of China
[13] Odette Cancer Centre; Mark Minden, University of Toronto, Toronto, Canada
[14] Hospital Universitari Germans Trias i Pujol, Catalunya, Spain
[15] Nantes University Hospital, Nantes, France
[16] Christopher Arthur, Royal North Shore Hospital, St Leonards, New South Wales, Australia - Source
Journal of clinical oncology. 2012, Vol 30, Num 21, pp 2670-2677, 8 p ; ref : 19 ref
- ISSN
- 0732-183X
- Scientific domain
- Medical oncology
- Publisher
- American Society of Clinical Oncology, Alexandria, VA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Age Anticancéreux Cancérologie Chimiothérapie Choix Cytarabine Dose faible Décitabine Essai clinique phase III Essai clinique Etude comparative Etude multicentrique Homme Leucémie aiguë myéloblastique Médecin Personne âgée Randomisation Soin de support Stade précoce Antipyrimidique Analogue de nucléoside Antimétabolite Azanucléoside Cancer Hémopathie maligne Pyrimidine nucléoside Traitement
- Keyword (en)
- Age Antineoplastic agent Cancerology Chemotherapy Choice Cytarabine Low dose Decitabine Phase III trial Clinical trial Comparative study Multicenter study Human Acute myelogenous leukemia Physician Elderly Randomization Supportive care Early stage Nucleoside analog Antimetabolic Azanucleoside Cancer Malignant hemopathy Pyrimidine nucleoside Treatment
- Keyword (es)
- Edad Anticanceroso Cancerología Quimioterapia Elección Citarabina Dosis débil Decitabina Ensayo clínico fase III Ensayo clínico Estudio comparativo Estudio multicéntrico Hombre Leucemia aguda mieloblástica Médico Anciano Aleatorización Cuidado de soporte Estadio precoz Análogo nucleósido Antimetabólito Azanucleósido Cáncer Hemopatía maligna Pirimidina nucleósido Tratamiento
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26186236
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1200/JCO.2011.38.9429 
https://dx.doi.org/10.1200/JCO.2011.38.9429
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