Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
- Author
- KOO, Bon-Kyoung1 ; SPIT, Maureen2 ; CLEVERS, Hans1 ; JORDENS, Ingrid2 ; LOW, Teck Y3 4 ; STANGE, Daniel E1 ; VAN DE WETERING, Marc1 ; ES, Johan H. Van1 ; MOHAMMED, Shabaz3 4 ; HECK, Albert J. R3 4 ; MAURICE, Madelon M2
[1] Hubrecht Institute, KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, Netherlands
[2] Department of Cell Biology, University Medical Center Utrecht, 3584 CX Utrecht, Netherlands
[3] Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CH Utrecht, Netherlands
[4] The Netherlands Proteomics Center, Padualaan 8, 3584CH Utrecht, Netherlands - Source
Nature (London). 2012, Vol 488, Num 7413, pp 665-669, 5 p ; ref : 31 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adénome Animal Cancérologie Carcinogenèse Endocytose Gène suppresseur tumeur Homme Ligases Mutation Récepteur biologique Souris Tumeur maligne Tumorigénicité Gène RNF43 Gène wnt Voie de signalisation Cancer Enzyme Génétique Mammalia Rodentia Tumeur bénigne Vertebrata
- Keyword (en)
- Adenoma Animal Cancerology Carcinogenesis Endocytosis Tumor suppressor gene Human Ligases Mutation Biological receptor Mouse Malignant tumor Tumorigenicity Signaling pathway Cancer Enzyme Genetics Mammalia Rodentia Benign neoplasm Vertebrata
- Keyword (es)
- Adenoma Animal Cancerología Carcinogénesis Endocitosis Gen supresor tumor Hombre Ligases Mutación Receptor biológico Ratón Tumor maligno Tumorigenicidad Vía de señalización Cáncer Enzima Genética Mammalia Rodentia Tumor benigno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Discipline
- Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26291253
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature11308 
https://dx.doi.org/10.1038/nature11308
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