Function and expression of the proton-coupled amino acid transporter PAT1 along the rat gastrointestinal tract: implications for intestinal absorption of gaboxadol
- Author
- BROBERG, M. L1 ; HOLM, R2 ; NIELSEN, C. U1 ; TØNSBERG, H1 2 ; FRØLUND, S1 ; EWON, K. B1 2 ; NIELSEN, A. L1 2 ; BRODIN, B1 ; JENSEN, A1 ; KALL, M. A3 ; CHRISTENSEN, K. V4
[1] Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
[2] Department of Preformulation, H. Lundbeck A/S, Copenhagen, Denmark
[3] Department of Early Development Pharmacokinetics, H. Lundbeck A/S, Copenhagen, Denmark
[4] Department of Neurodegeneration 2, H. Lundbeck A/S, Copenhagen, Denmark - Source
British journal of pharmacology. 2012, Vol 167, Num 3, pp 654-665, 12 p ; ref : 1 p.1/4
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- PAT1 (SLC36A1) colon absorption gaboxadol in vivo transportertransporter-mediated pharmacokinetics small intestinal absorption
- Keyword (fr)
- Absorption Aminoacide Animal Côlon Estomac Gaboxadol Gastrointestinal In vivo Intestin Pharmacocinétique Protéine transport Psychotrope Rat Tranquillisant Agoniste Appareil digestif Mammalia Rodentia Récepteur gabaergique A Récepteur gabaergique Stimulant gabaergique Vertebrata
- Keyword (en)
- Absorption Aminoacid Animal Colon Stomach Gaboxadol Gastrointestinal In vivo Gut Pharmacokinetics Carrier protein Psychotropic Rat Tranquillizer Agonist Digestive system Mammalia Rodentia Gabaergic receptor A Gabaergic receptor Gabaergic agonist Vertebrata
- Keyword (es)
- Absorción Aminoácido Animal Colón Estómago Gaboxadol Gastrointestinal In vivo Intestino Farmacocinética Proteína transportador Psicotropo Rata Tranquilizante Agonista Aparato digestivo Mammalia Rodentia Receptor gabaminérgico A Receptor gabaminérgico Estimulante gabaérgico Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26355034
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1476-5381.2012.02030.x 
https://dx.doi.org/10.1111/j.1476-5381.2012.02030.x
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