New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells
- Author
- REITER, Christoph1 ; HERRMANN, Astrid1 ; CAPCI, Aysun1 ; EFFERTH, Thomas2 ; TSOGOEVA, Svetlana B1
[1] Institute of Organic Chemistry I, University of Erlangen-Nuremberg, Henkestrasse 42, 91054 Erlangen, Germany
[2] Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128 Mainz, Germany - Source
Bioorganic & medicinal chemistry. 2012, Vol 20, Num 18, pp 5637-5641, 5 p ; ref : 27 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Artesunic acid Chemotherapy Drug design Homodimers Linker Multidrug resistance Reactive oxygen species
- Keyword (fr)
- Apoptose Chimiothérapie Espèces réactives de l'oxygène In vitro Leucémie Mort cellulaire Médicament Résistance multiple Réversibilité Stress oxydatif Bras espaceur Oxygène actif Cancer Hémopathie maligne Traitement
- Keyword (en)
- Apoptosis Chemotherapy Reactive oxygen species In vitro Leukemia Cell death Drug Multiple resistance Reversibility Oxidative stress Spacer arm Cancer Malignant hemopathy Treatment
- Keyword (es)
- Apoptosis Quimioterapia Especies reactivas del oxígeno In vitro Leucemia Muerte celular Medicamento Resistencia múltiple Reversibilidad Estrés oxidativo Cáncer Hemopatía maligna Tratamiento
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26408151
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2012.07.015 
https://dx.doi.org/10.1016/j.bmc.2012.07.015
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