Drug-induced Cardiac Mitochondrial Toxicity and Protection: From Doxorubicin to Carvedilol
- Author
- PEREIRA, Gonçalo C1 ; SILVA, Ana M1 ; DIOGO, Catia V1 ; CARVALHO, Filipa S1 ; MONTEIRO, Pedro2 ; OLIVEIRA, Paulo J1
[1] Center for Neuroscience and Cell Biology, Department of Life Sciences, University of Coimbra, Portugal
[2] Department of Cardiology of the Coimbra University Hospital and Medical School, Coimbra, Portugal - Issue title
- Mitochondria as a Pharmacological Target: A Clue for Efficacy and a Reason for Toxicity
- Author (monograph)
- APOSTOLOVA, Nadezda (Editor)1
[1] CIBERehd-Universitat de València, Facultad de Medicina, Avda Blasco Ibañez n.15-17, 46010 Valencia, Spain - Source
Current pharmaceutical design (Print). 2011, Vol 17, Num 20, pp 2113-2129, 17 p ; ref : 199 ref
- ISSN
- 1381-6128
- Scientific domain
- Pharmacology drugs
- Publisher
- Bentham, Sharjah
- Publication country
- United Arab Emirates
- Document type
- Article
- Language
- English
- Author keyword
- Cardioprotection carvedilol doxorubicin heart mitochondria toxicity
- Keyword (fr)
- Antibiotique Anticancéreux Antihypertenseur Article synthèse Cardioprotecteur Carvédilol Coeur Doxorubicine Mitochondrie Toxicité Vasodilatateur Antagoniste Anthracyclines Appareil circulatoire Bloquant α-adrénergique Bloquant β-adrénergique DNA topoisomerase (ATP-hydrolysing) Enzyme Inhibiteur de la topoisomérase II Inhibiteur enzyme Isomerases Récepteur α1-adrénergique Récepteur β1-adrénergique Récepteur β2-adrénergique
- Keyword (en)
- Antibiotic Antineoplastic agent Antihypertensive agent Review Cardioprotective agent Carvedilol Heart Doxorubicin Mitochondria Toxicity Vasodilator agent Antagonist Anthracyclins Circulatory system Alpha blocking agent Beta blocking agent DNA topoisomerase (ATP-hydrolysing) Enzyme Topoisomerase II inhibitor Enzyme inhibitor Isomerases α1-Adrenergic receptor β1-Adrenergic receptor β2-Adrenergic receptor
- Keyword (es)
- Antibiótico Anticanceroso Antihipertensivo Artículo síntesis Cardioprotector Carvedilol Corazón Doxorubicina Mitocondria Toxicidad Vasodilatador Antagonista Antraciclinas Aparato circulatorio Bloqueador α-adrenérgico Bloqueador β-adrenérgico DNA topoisomerase (ATP-hydrolysing) Enzima Inhibidor topoisomerase II Inhibidor enzima Isomerases Receptor α1-adrenérgico Receptor β1-adrenérgico Receptor β2-adrenérgico
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26420381
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/138161211796904812 
https://dx.doi.org/10.2174/138161211796904812
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