Host―microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- Autor
- JOSTINS, Luke1 ; RIPKE, Stephan2 3 ; ESSERS, Jonah13 ; MITROVIC, Mitja14 15 ; NING, Kaida12 ; CLEYNEN, Isabelle16 ; THEATRE, Emilie17 18 ; SPAIN, Sarah L19 ; RAYCHAUDHURI, Soumya20 21 22 ; GOYETTE, Philippe23 ; ZHI WEI24 ; ABRAHAM, Clara12 ; WEERSMA, Rinse K4 ; ACHKAR, Jean-Paul25 ; AHMAD, Tariq; AMININEJAD, Leila; ANANTHAKRISHNAN, Ashwin N; ANDERSEN, Vibeke; ANDREWS, Jane M; BAIDOO, Leonard5 ; BALSCHUN, Tobias; BAMPTON, Peter A; BITTON, Alain; DUERR, Richard H5 6 ; BOUCHER, Gabrielle23 ; BRAND, Stephan; BÜNING, Carsten; COHAIN, Ariella; CICHON, Sven; D'AMATO, Mauro; DE JONG, Dirk4 ; DEVANEY, Kathy L; DUBINSKY, Marla; EDWARDS, Cathryn; MCGOVERN, Dermot P7 8 ; ELLINGHAUS, David; FERGUSON, Lynnette R; FRANCHIMONT, Denis; FRANSEN, Karin5 ; GEARRY, Richard; GEORGES, Michel17 ; GIEGER, Christian; GLAS, Jürgen; HARITUNIANS, Talin8 ; HART, Ailsa; HUI, Ken Y9 ; HAWKEY, Chris; HEDL, Matija12 ; XINLI HU20 ; KARLSEN, Tom H; KUPCINSKAS, Limas; KUGATHASAN, Subra; LATIANO, Anna; LAUKENS, Debby; LAWRANCE, Ian C; LEES, Charlie W; LEE, James C10 ; PHILIP SCHUMM, L11 ; SHARMA, Yashoda12 ; ANDERSON, Carl A1
[1] Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, United Kingdom
[2] Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States
[3] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States
[4] Department of Gastroenterologyand Hepatology, University of Groningen and University Medical Center Groningen, Groningen 9700 RB, Netherlands
[5] Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, United States
[6] Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, United States
[7] F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Los Angeles, California 90048, United States
[8] Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States
[9] Department of Genetics, Yale School of Medicine, New Haven, Connecticut 06520, United States
[10] Inflammatory Bowel Disease Research Group, Adden brooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, United Kingdom
[11] Department of Health Studies, University of Chicago, Chicago, Illinois 60637, United States
[12] Department of Internal Medicine, Section of Digestive Diseases, Yale School of Medicine, New Haven, Connecticut 06520, United States
[13] Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States
[14] University of Maribor, Faculty of Medicine, Center for Human Molecular Genetics and Pharmacogenomics, Maribor 2000, Slovenia
[15] University Medical Center Groningen, Department of Genetics, Groningen 9700 RB, Netherlands
[16] Department of Clinical and Experimental Medicine, Gastroenterology section, KU Leuven, Leuven 3000, Belgium
[17] Unit of Animal Genomics, Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA-R) and Faculty of Veterinary Medicine, University of Liege, Liege 4000, Belgium
[18] Division of Gastroenterology, Centre Hospitalier Universitaire, Université de Liege, Liege 4000, Belgium
[19] Department of Medical and Molecular Genetics, Division of Genetics and Molecular Medicine, King's College London School of Medicine, Guy's Hospital, London SE1 9RT, United Kingdom
[20] Division of Rheumatology Immunologyand Allergy, Brigham and Women's Hospital, Boston, Massachusetts 02115, United States
[21] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, United States
[22] Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts 02115, United States
[23] Université de Montreal and the Montreal Heart Institute, Research Center, Montreal, Quebec H1T 1C8, Canada
[24] Department of Computer Science, New Jersey Institute of Tech nology, Newark, New Jersey 07102, United States
[25] Department of Gastroenterology & Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio 44195, United States - Fuente
Nature (London). 2012, Vol 491, Num 7422, pp 119-124, 6 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Campo Científico
- Multidisciplinary
- Editor
- Nature Publishing Group, London
- País de la publicación
- United Kingdom
- Tipo de documento
- Article
- Idioma
- English
- Palabra clave (fr)
- Allèle Chronique Connaissance Contrôle Entérite de Crohn Expression génique Génome Historique Homme Maladie héréditaire Mycobacterium Mycobactériose Pathogénie Phénotype Prévalence Psoriasis Rectocolite ulcérohémorragique Réseau Spondylarthrite ankylosante Maladie inflammatoire de l'intestin Europe Actinomycetes Bactérie Bactériose Epidémiologie Infection Maladie inflammatoire Mycobacteriaceae Mycobacteriales Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie de la peau Pathologie du rachis Pathologie du système ostéoarticulaire Prévention Rhumatisme inflammatoire Spondylarthropathie
- Palabra clave (in)
- Allele Chronic Knowledge Check Crohn disease Gene expression Genome Case history Human Genetic disease Mycobacterium Mycobacterial infection Pathogenesis Phenotype Prevalence Psoriasis Ulcerative colitis Network Ankylosing spondylitis Inflammatory bowel disease Europe Actinomycetes Bacteria Bacteriosis Epidemiology Infection Inflammatory disease Mycobacteriaceae Mycobacteriales Digestive diseases Intestinal disease Skin disease Spine disease Diseases of the osteoarticular system Prevention Inflammatory joint disease Spondylarthropathy
- Palabra clave (es)
- Alelo Crónico Conocimiento Control Enteritis Crohn Expresión genética Genoma Estudio histórico Hombre Enfermedad hereditaria Mycobacterium Micobacteriosis Patogenia Fenotipo Prevalencia Psoriasis Rectocolitis ulcerohemorrágica Red Espondiloartritis anquilosante Enfermedad inflamatoria intestinal Europa Actinomycetes Bacteria Bacteriosis Epidemiología Infección Enfermedad inflamatoria Mycobacteriaceae Mycobacteriales Aparato digestivo patología Intestino patología Piel patología Raquis patología Sistema osteoarticular patología Prevención Reumatismo inflamatorio Espondilartropatia
- Clasificación
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B08 Dermatology / 002B08D Psoriasis. Parapsoriasis. Lichen
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B03 Other diseases. Semiology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15D Inflammatory joint diseases
- Disciplina
- Dermatology Gastroenterology. Liver. Pancreas. Abdomen Osteoarticular pathology
- Procedencia
- Inist-CNRS
- Base de datos
- PASCAL
- Identificador INIST
- 26554322
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature11582 
https://dx.doi.org/10.1038/nature11582
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Acceso mediante Europe PubMed Central
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Acceso mediante arXiv
