Large-scale prediction of drug―target interactions using protein sequences and drug topological structures
- Author
- CAO, Dong-Sheng1 ; SHAO LIU3 ; XU, Qing-Song2 ; LU, Hong-Mei1 ; HUANG, Jian-Hua1 ; HU, Qian-Nan4 ; LIANG, Yi-Zeng1
[1] Research Center of Modernization of Traditional Chinese Medicines, Central South University, Changsha 410083, China
[2] School of Mathematical Sciences and Computing Technology, Central South University, Changsha 410083, China
[3] Xiangya Hospital, Central South University, Changsha 410008, China
[4] Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China - Source
Analytica chimica acta. 2012, Vol 752, pp 1-10, 10 p ; ref : 83 ref
- CODEN
- ACACAM
- ISSN
- 0003-2670
- Scientific domain
- Analytical chemistry
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Chemoinformatics Drug-target interactions Extended structure-activity relationship Molecular fingerprint Support vector machines
- Keyword (fr)
- Canal ionique Cible Compatibilité Echelle grande Enzyme Groupe fonctionnel Homme Identification Interaction moléculaire Molécule Médicament Méthode fingerprint Propriété physicochimique Protéine G Précision Prédiction Récepteur nucléaire Sous structure Support Utilisation Vecteur
- Keyword (en)
- Ionic channel Target Compatibility Large scale Enzyme Functional group Human Identification Molecular interaction Molecules Drug Fingerprint method Physicochemical properties G protein Accuracy Prediction Nuclear receptor Substructure Support Use Vector
- Keyword (es)
- Canal iónico Blanco Compatibilidad Escala grande Enzima Grupo funcional Hombre Identificación Interacción molecular Molécula Medicamento Método fingerprint Propiedad fisicoquímica Proteína G Precisión Predicción Receptor nuclear Subestructura Soporte Uso Vector
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A03 Molecular biophysics / 002A03H Intermolecular phenomena / 002A03H01 Interactions. Associations
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04F Cell structures and functions / 002A04F02 Cell membranes. Ionic channels. Membrane pores
- Discipline
- Analytical chemistry Molecular and cell biology Molecular biophysics
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26565036
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.aca.2012.09.021 
https://dx.doi.org/10.1016/j.aca.2012.09.021
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