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A Safety Run-In and Randomized Phase 2 Study of Cilengitide Combined With Chemoradiation for Newly Diagnosed Glioblastoma (NABTT 0306)

Author
NABORS, L. Burt1 ; MIKKELSEN, Thomas2 ; FISHER, Joy D11 12 ; GROSSMAN, Stuart A13 ; HEGI, Monika E3 ; XIAUBU YE4 ; BATCHELOR, Tracy5 ; LESSER, Glenn6 ; PEEREBOOM, David7 ; ROSENFELD, Myrna R8 ; OLSEN, Jeff9 ; BREM, Steve10
[1] Brain Tumor Treatment and Research Program, University of Alabama at Birmingham, Birmingham, Alabama, United States
[2] Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, United States
[3] Department of Neurosurgery, University Hospital and University of Lausanne, Lausanne, Switzerland
[4] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States
[5] Department of Neuro-Oncology, Massachusetts General Hospital, Cambridge, Massachusetts, United States
[6] Department of Hematology/Oncology, Wake Forest Medical Center, Wake Forest, North Carolina, United States
[7] Brain Tumor/Neuro-Oncology Center, The Cleveland Clinic, Cleveland, Ohio, United States
[8] Deparment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
[9] Department of Neurosurgery, Emory University, Atlanta, Georgia, United States
[10] Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
[11] Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, New Approaches to Brain Tumor Therapy Consortium, Baltimore, Maryland, United States
[12] Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama, United States
[13] Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
New Approaches to Brain Tumor Therapy (NABTT) Central Nervous System Consortium
Source

Cancer. 2012, Vol 118, Num 22, pp 5601-5607, 7 p ; ref : 15 ref

CODEN
CANCAR
ISSN
0008-543X
Scientific domain
Medical oncology
Publisher
Wiley-Blackwell, Hoboken, NJ
Publication country
United States
Document type
Article
Language
English
Author keyword
angiogenesis cilengitide clinical trial glioblastoma integrin
Keyword (fr)
Angiogenèse Antiangiogénique Cancérologie Chimiothérapie Cilengitide Essai clinique phase II Essai clinique Glioblastome Intégrine Néovascularisation Protéine CAM Radiothérapie Randomisation Stade précoce Traitement associé Cancer Gliome malin Pathologie du système nerveux central Pathologie du système nerveux Peptide Traitement Tumeur maligne
Keyword (en)
Angiogenesis Antiangiogenic agent Cancerology Chemotherapy Cilengitide Phase II trial Clinical trial Glioblastoma Integrin Neovascularization Cell adhesion molecule Radiotherapy Randomization Early stage Combined treatment Cancer Malignant glioma Central nervous system disease Nervous system diseases Peptides Treatment Malignant tumor
Keyword (es)
Angiogénesis Antiangiogenico Cancerología Quimioterapia Cilengitida Ensayo clínico fase II Ensayo clínico Glioblastoma Integrina Neovascularización Proteína CAM Radioterapia Aleatorización Estadio precoz Tratamiento asociado Cáncer Glioma maligno Sistema nervosio central patología Sistema nervioso patología Péptido Tratamiento Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses

Discipline
Neurology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
26569634

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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