Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
- Author
- LOPEZ-GIRONA, A1 ; MENDY, D1 ; MAHMOUDI, A1 ; CATHERS, B1 ; RYCHAK, E1 ; GAIDAROVA, S1 ; CHEN, R3 ; SCHAFER, P. H3 ; HANDA, H2 ; DANIEL, T. O1 ; EVANS, J. F1 ; CHOPRA, R3 ; ITO, T2 ; MILLER, K1 ; GANDHI, A. K3 ; KANG, J3 ; KARASAWA, S2 ; GARMEL, G1 ; JACKSON, P1 ; ABBASIAN, M1
[1] Celgene, San Diego, CA, United States
[2] Solutions Research Laboratory, Tokyo Institute of Technology, Tokyo, Japan
[3] Celgene Corp, Summit, NJ, United States - Source
Leukemia. 2012, Vol 26, Num 11, pp 2326-2335, 10 p ; ref : 33 ref
- CODEN
- LEUKED
- ISSN
- 0887-6924
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Nature Publishing Group, Avenel, NJ
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- antiproliferative cereblon immunomodulatory lenalidomide myeloma pomalidomide
- Keyword (fr)
- Activité biologique Anticancéreux Ciblage Hématologie Immunomodulateur Immunomodulation Lénalidomide Myélome Pomalidomide Protéine A Hémopathie lymphoïde B Hémopathie maligne lymphoïde Cancer Hémopathie maligne Immunoglobulinopathie Immunopathologie Syndrome lymphoprolifératif
- Keyword (en)
- Biological activity Antineoplastic agent Targeting Hematology Immunomodulator Immunomodulation Lenalidomide Myeloma Pomalidomide Protein A B cell neoplasm Lymphoid neoplasm Cancer Malignant hemopathy Immunoglobulinopathy Immunopathology Lymphoproliferative syndrome
- Keyword (es)
- Actividad biológica Anticanceroso Blancado Hematología Inmunomodulador Inmunomodulación Lenalidomide Mieloma Pomalidomida Proteína A Cáncer Hemopatía maligna Inmunoglobulinopatía Inmunopatología Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology / 002B06D Immunodeficiencies. Immunoglobulinopathies / 002B06D02 Immunoglobulinopathies
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases Immunopathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26597824
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/leu.2012.119 
https://dx.doi.org/10.1038/leu.2012.119
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