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The Pseudomonas aeruginosa exotoxin A translocation domain facilitates the routing of CPP―protein cargos to the cytosol of eukaryotic cells

Author
MOHAMMED, Arshiya F1 3 ; ABDUL-WAHID, Aws1 3 ; HUANG, Eric H.-B3 ; BOLEWSKA-PEDYCZAK, Eleonora3 ; CYDZIK, Marzena3 ; BROAD, Amaalia E2 ; GARIEPY, Jean1 2 3
[1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
[2] Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada
[3] Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
Source

Journal of controlled release. 2012, Vol 164, Num 1, pp 58-64, 7 p ; ref : 40 ref

CODEN
JCREEC
ISSN
0168-3659
Scientific domain
Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Cell penetrating peptide Cellular internalization Delivery of protein therapeutics Endosomal escape Exotoxin A translocation domain
Keyword (fr)
Cytosol Exotoxine In vitro Internalisation Protéine fusion Protéine Pseudomonas aeruginosa Technologie pharmaceutique Translocation Transport intracellulaire Echappement de l'endosome Exotoxine A Peptide pénétrant CPP Bactérie Pseudomonadaceae Pseudomonadales Toxine
Keyword (en)
Cytosol Exotoxin In vitro Internalization Fusion protein Protein Pseudomonas aeruginosa Pharmaceutical technology Translocation Intracellular transport Endosomal escape Cell penetrating peptide Bacteria Pseudomonadaceae Pseudomonadales Toxin
Keyword (es)
Citosol Exotoxina In vitro Internalización Proteína fusionada Proteína Pseudomonas aeruginosa Tecnología farmacéutica Translocación Transporte intracelular Escape endosomal Péptido CPP Bacteria Pseudomonadaceae Pseudomonadales Toxina
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A01 Physicochemical properties. Structure-activity relationships

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
26664083

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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