The Impact of Sialic Acids on the Pharmacokinetics of a PEGylated Erythropoietin
- Author
- LIMING LIU1 ; HUIJUAN LI2 ; HAMILTON, Stephen R2 ; GOMATHINAYAGAM, Sujatha2 ; RAYFIELD, William J3 ; VAN MAANEN, Marc4 ; YIN, Kuo-Chang5 ; LAURA HONG5 ; PRUEKSARITANONT, Thomayant1
[1] Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486, United States
[2] Biologics Discovery (GlycoFi, Merck), Merck Research Laboratories, Lebanon, New Hampshire 03766, United States
[3] Protein Purification Development, Merck Research Laboratories Rahway, New Jersey 07065, United States
[4] Project Leadership and Global Systems, Merck & Company, Inc., West Point, Pennsylvania 19486, United States
[5] Vaccine Analytical Development, Merck Research Laboratories, West Point, Pennsylvania 19486, United States - Source
Journal of pharmaceutical sciences. 2012, Vol 101, Num 12, pp 4414-4418, 5 p ; ref : 15 ref
- CODEN
- JPMSAE
- ISSN
- 0022-3549
- Scientific domain
- Pharmacology drugs
- Publisher
- American Pharmaceutical Association, Washington, DC
/
Wiley, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- biotechnology clearance glycosylation pegylation pharmacokinetics
- Keyword (fr)
- Acide sialique Biotechnologie Clairance Erythropoïétine Forme pégylée Glycosylation Pharmacocinétique Technologie pharmaceutique Agent stimulant l'érythropoïèse Polypeptide
- Keyword (en)
- Sialic acid Biotechnology Clearance Erythropoietin Pegylated form Glycosylation Pharmacokinetics Pharmaceutical technology Polypeptide
- Keyword (es)
- Siálico ácido Biotecnología Depuración Eritropoyetina Forma pegilada Glicosilación Farmacocinética Tecnología farmacéutica Polipéptido
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26669401
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jps.23320 
https://dx.doi.org/10.1002/jps.23320
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