Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells
- Author
- LI YUAN1 ; JING WANG1 ; HAIFANG XIAO1 ; CHUNXIA XIAO1 ; YUTANG WANG1 ; XUEBO LIU1
[1] Laboratory of Nutrition and Functional Factors, College of Food Science and Engineering, Northwest A & F University, Yangling, China - Source
Toxicology and applied pharmacology. 2012, Vol 265, Num 1, pp 83-92, 10 p ; ref : 3/4 p
- CODEN
- TXAPA9
- ISSN
- 0041-008X
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Isoorientin Mitochondrial stress NO PI3K/Akt ROS
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Apoptose Cellule tumorale In vitro Inhibiteur Inhibition Mitochondrie Mort cellulaire Stress Transduction signal Trouble fonctionnel Lignée HEPG2 Voie de signalisation Appareil digestif Enzyme Foie Homme Hépatocyte Lignée cellulaire Transferases
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Apoptosis Tumor cell In vitro Inhibitor Inhibition Mitochondria Cell death Stress Signal transduction Dysfunction Signaling pathway Digestive system Enzyme Liver Human Hepatocyte Cell line Transferases
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Apoptosis Célula tumoral In vitro Inhibidor Inhibición Mitocondria Muerte celular Estrés Transducción señal Trastorno funcional Vía de señalización Aparato digestivo Enzima Hígado Hombre Hepatocito Línea celular Transferases
- Classification
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26679936
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.taap.2012.09.022 
https://dx.doi.org/10.1016/j.taap.2012.09.022
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