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'Human-on-a-chip' Developments: A Translational Cutting- edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man?

Author
MARX, Uwe1 ; WALLES, Heike2 ; HOFFMANN, Silke1 ; LINDNER, Gerd1 ; HORLAND, Reyk1 ; SONNTAG, Frank3 ; KLOTZBACH, Udo3 ; SAKHAROV, Dmitry4 ; TONEVITSKY, Alexander5 ; LAUSTER, Roland1
[1] Technische Universität Berlin, Department of Biotechnology, Berlin, Germany
[2] Universität Würzburg, Würzburg, Germany
[3] Fraunhofer-Institut fur Werkstoff- und Strahltechnik IWS, Dresden, Germany
[4] SRC Bioclinicum, Moscow, Russian Federation
[5] Moscow State University, Moscow, Russian Federation
Source

ATLA. Alternatives to laboratory animals. 2012, Vol 40, Num 5, pp 235-257, 23 p ; ref : 188 ref

ISSN
0261-1929
Scientific domain
Medical laboratory techniques; Toxicology
Publisher
Fund for the Replacement of Animals in Medical Experiments, Nottingham
Publication country
United Kingdom
Document type
Article
Language
Russian
Author keyword
3-D culture dynamic bioreactors microfluidics microsystems organ-on-a-chip toxicity pathway
Keyword (fr)
Adulte Animal laboratoire Bioréacteur Bord Dynamique Développement Efficacité Evaluation Homme Mâle Méthode alternative Organe Systémique Toxicité Traduction génétique
Keyword (en)
Adult Laboratory animal Bioreactor Edge Dynamics Development Efficiency Evaluation Human Male Alternative method Organ Systemic Toxicity Genetic translation
Keyword (es)
Adulto Animal laboratorio Biorreactor Borde Dinámica Desarrollo Eficacia Evaluación Hombre Macho Método alternativo Organo Sistémico Toxicidad Traducción genética
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology

Discipline
Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
26680566

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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