Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxy-phenyl)-5-aryl thiazoles as anticancer agents
- Author
- ROMAGNOLI, Romeo1 ; GIOVANNI BARALDI, Pier1 ; BASSO, Giuseppe4 ; VIOLA, Giampietro4 ; SALVADOR, Maria Kimatrai1 ; CAMACHO, M. Encarnacion1 ; PRETI, Delia1 ; AGHAZADEH TABRIZI, Mojgan1 ; BASSETTO, Marcella2 ; BRANCALE, Andrea2 ; HAMEL, Ernest3 ; BORTOLOZZI, Roberta4
[1] Dipartimento di Scienze Farmaceutiche, Via Fossato di Mortara 17-19, Università di Ferrara, 44121 Ferrara, Italy
[2] School of Pharmary and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, United Kingdom
[3] Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, MD 21702, United States
[4] Dipartimento di Salute della Donna e del Bambino, Laboratorio di Oncoematologia, Università di Padova, 35131 Padova, Italy - Source
Bioorganic & medicinal chemistry. 2012, Vol 20, Num 24, pp 7083-7094, 12 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Colchicine site Combretastatin-A4 Thiazole Tubulin
- Keyword (fr)
- Activité biologique Alcaloïde Anticancéreux Antimitotique Antitubuline Apoptose Colchicine Dérivé du stilbène Dérivé du thiazole Hypouricémiant Mort cellulaire Synthèse chimique Thiazole Tubuline Benzo[a]heptalène dérivé Benzoheptalène Combretastatine A4 dérivé Combrétastatine A-4 Combrétastatine dérivé
- Keyword (en)
- Biological activity Alkaloid Antineoplastic agent Antimitotic Antitubulin Apoptosis Colchicine Stilbene derivatives Thiazole derivatives Hypouricemic agent Cell death Chemical synthesis Thiazole Tubulin Combretastatin derivative
- Keyword (es)
- Actividad biológica Alcaloide Anticanceroso Antimitótico Antitubulina Apoptosis Colchicina Estilbeno derivado Tiazol derivado Hipouricemiante Muerte celular Síntesis química Tiazol Tubulina Combretastatina derivado
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26727240
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2012.10.001 
https://dx.doi.org/10.1016/j.bmc.2012.10.001
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