FMRP targets distinct mRNA sequence elements to regulate protein expression
- Author
- ASCANO, Manuel1 ; MUKHERJEE, Neelanjan2 ; WILLIAMS, Zev1 3 ; OHLER, Uwe2 ; TUSCHL, Thomas1 ; BANDARU, Pradeep1 ; MILLER, Jason B1 ; NUSBAUM, Jeffrey D1 ; CORCORAN, David L2 ; LANGLOIS, Christine3 ; MUNSCHAUER, Mathias1 ; DEWELL, Scott4 ; HAFNER, Markus1
[1] Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York 10065, United States
[2] Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina 27708, United States
[3] Program for Early and Recurrent Pregnancy Loss, Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, New York 10461, United States
[4] Genomics Resource Center, The Rockefeller University, New York, New York 10065, United States - Source
Nature (London). 2012, Vol 492, Num 7429, pp 382-386, 5 p ; ref : 46 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Arriération mentale Autisme Culture cellulaire Distribution Femelle Homme Mâle Ménopause précoce Protéine liaison RNA messager Régulation Site fixation Souris Syndrome du chromosome X fragile Séquence aminoacide Traitement Trouble envahissant du développement Trouble neurologique Trouble psychiatrique Déficience intellectuelle Fragilité chromosomique Mammalia Pathologie du système nerveux Rodentia Trouble du développement Vertebrata
- Keyword (en)
- Animal Mental retardation Autism Cell culture Distribution Female Human Male Premature menopause Binding protein Messenger RNA Regulation(control) Binding site Mouse Fragile X syndrome Aminoacid sequence Treatment Pervasive developmental disorder Neurological disorder Mental disorder Intellectual deficiency Chromosome fragility Mammalia Nervous system diseases Rodentia Developmental disorder Vertebrata
- Keyword (es)
- Animal Retraso mental Autismo Cultivo celular Distribución Hembra Hombre Macho Menopausia precoz Proteína enlace RNA mensajero Regulación Sitio fijación Ratón X frágil síndrome Secuencia aminoácido Tratamiento Disturbio invasor del desarrollo Trastorno neurológico Trastorno psiquiátrico Deficiencia intelectual Fragilidad cromosómica Mammalia Sistema nervioso patología Rodentia Trastorno desarrollo Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C12 Intellectual deficiency
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18D Child clinical studies / 002B18D04 Developmental disorders / 002B18D04B Infantile autism
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20H Puberal and climacteric disorders (male and female)
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03L Intellectual deficiency
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D04 Child clinical studies / 770-D04D Developmental disorders / 770-D04D02 Infantile autism
- Discipline
- Gynecology. Andrology. Obstetrics Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 26751650
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature11737 
https://dx.doi.org/10.1038/nature11737
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