The human OPA1deITTAG mutation induces premature age-related systemic neurodegeneration in mouse
- Author
- SARZI, Emmanuelle1 ; ANGEBAULT, Claire2 ; RENOU, Jean-Pierre3 ; JING WANG1 ; DELETTRE, Cécile1 ; BRABET, Philippe1 ; PUEL, Jean-Luc1 ; HAMEL, Christian P1 ; REYNIER, Pascal2 ; LENAERS, Guy1 ; SEVENO, Marie1 ; GUEGUEN, Naïg2 ; CHAIX, Benjamin1 ; BIELICKI, Guy3 ; BODDAERT, Nathalie4 ; MAUSSET-BONNEFONT, Anne-Laure5 ; CAZEVIEILLE, Chantal6 ; RIGAU, Valérie7
[1] Institut des Neurosciences de Montpellier, INSERM U1051, Université Montpellier I et II 34091 Montpellier, France
[2] Departement de Biochimie et de Génétique, UMR CNRS 6214, INSERM U1083, CHU d'Angers, 49000 Angers, France
[3] Plateforme de Resonance Magnétique des Systemes Biologiques, Clermont-Theix, INRA UR370, 63122 Saint Genes Champanelle, France
[4] Service de Radiologie Pédiatrique, Hôpital Necker Enfants Malades, 75743 Paris, France
[5] Institut des Neurosciences de Montpellier, INSERM U844, Université Montpellier I et II 34091 Montpellier, France
[6] Centre de Ressources en Imagerie Cellulaire, Université Montpellier I 34093 Montpellier, France
[7] Service d'Anatomie et Cytologie Pathologique, CHU Guy de Chauliac, 34295 Montpellier, France - Source
Brain. 2012, Vol 135, pp 3599-3613, 15 p ; 12 ; ref : 1 p.1/4
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- dominant optic atrophy mitochondria mouse model neurodegeneration respiratory chain complexes
- Keyword (fr)
- Animal Ataxie optique Atrophie du nerf optique Chaîne respiratoire Homme Mitochondrie Modèle animal Mutation Pathologie du système nerveux Prématuré Souris Mammalia Pathologie de l'encéphale Pathologie de l'oeil Pathologie des nerfs crâniens Pathologie du système nerveux central Rodentia Trouble neurologique Vertebrata
- Keyword (en)
- Animal Optic ataxia Optic nerve atrophy Respiratory chain Human Mitochondria Animal model Mutation Nervous system diseases Premature Mouse Mammalia Cerebral disorder Eye disease Cranial nerve disease Central nervous system disease Rodentia Neurological disorder Vertebrata
- Keyword (es)
- Animal Ataxia óptica Atrofia nervio óptico Cadena respiratoria Hombre Mitocondria Modelo animal Mutación Sistema nervioso patología Prematuro Ratón Mammalia Encéfalo patología Ojo patología Nervio craneal patología Sistema nervosio central patología Rodentia Trastorno neurológico Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26780531
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/brain/aws303 
https://dx.doi.org/10.1093/brain/aws303
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