Mechanistic links between oxidative/ nitrosative stress and tumor necrosis factor alpha in letrozole-induced murine polycystic ovary: Biochemical and pathological evidences for beneficial effect of pioglitazone

Author

REZVANFAR, M. A^{1 2} ; REZVANFAR, M. A¹ ; AHMADI, A³ ; SHOJAEI SAADI, H. A⁴ ; BAEERI, M¹ ; ABDOLLAHI, M^{1 2 5}
[1] Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of
[2] Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of
[3] Laboratory of Histology and Embryology, Department of Basic Science, Faculty of Veterinary Medicine, Urmia University, Iran, Islamic Republic of
[4] Production Animal Health Department, Faculty of Veterinary Medicine, University of Calgary, Alberta, Canada
[5] Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of

Source

Human & experimental toxicology. 2012, Vol 31, Num 9, pp 887-897, 11 p ; ref : 73 ref

ISSN

0960-3271

Scientific domain

Toxicology

Publisher

Sage Publications, London

Publication country

United Kingdom

Document type

Article

Language

English

Author keyword

hyperandrogenism inflammatory mediators letrozole oxidative stress pioglitazone polycystic ovary

Keyword (fr)

Animal Anticancéreux Facteur nécrose tumorale α Hyperandrogénie Hypoglycémiant Inflammation Létrozole Ovaire polykystique Pathologie expérimentale Pioglitazone Souris Stress oxydatif Toxicité Agoniste Antihormone Antioestrogène Composé non stéroïde Cytokine Dérivé d'azole Dérivé de la thiazolidinedione Dérivé du triazole Endocrinopathie Enzyme Estrogen synthase Inhibiteur de l'aromatase Inhibiteur enzyme Kyste Mammalia Pathologie de l'appareil génital femelle Pathologie des ovaires Rodentia Récepteur PPAR-γ Stérilité femelle Tumeur bénigne Vertebrata

Keyword (en)

Animal Antineoplastic agent Tumor necrosis factor α Hyperandrogenism Hypoglycemic agent Inflammation Letrozole Polycystic ovary Experimental disease Pioglitazone Mouse Oxidative stress Toxicity Agonist Antihormone Antiestrogen Non steroid compound Cytokine Azole derivatives Thiazolidinedione derivatives Triazole derivatives Endocrinopathy Enzyme Estrogen synthase Aromatase inhibitor Enzyme inhibitor Cyst Mammalia Female genital diseases Ovarian diseases Rodentia PPAR-γ receptor Female sterility Benign neoplasm Vertebrata

Keyword (es)

Animal Anticanceroso Factor necrosis tumoral α Hiperandrogenismo Hipoglicemiante Inflamación Letrozol Ovario poliquístico Patología experimental Pioglitazona Ratón Estrés oxidativo Toxicidad Agonista Antihormona Antiestrógeno Compuesto no esteroide Citoquina Azol derivado Tiazolidinediona derivado Triazol derivado Endocrinopatía Enzima Estrogen synthase Inhibidor aromatase Inhibidor enzima Quiste Mammalia Aparato genital hembra patología Ovario patología Rodentia Receptor PPAR-γ Esterilidad femenina Tumor benigno Vertebrata

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20C Female genital diseases / 002B20C01 Non tumoral diseases

Discipline

Gynecology. Andrology. Obstetrics Toxicology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

26875486

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS