The accumulations of HIF-1α and HIF-2α by JNK and ERK are involved in biphasic effects induced by different levels of arsenite in human bronchial epithelial cells
- Author
- YUAN XU1 2 ; YUAN LI1 2 ; HUIQIAO LI3 ; YING PANG1 2 ; YUE ZHAO1 2 ; RONGRONG JIANG1 2 ; LU SHEN1 2 ; JIANWEI ZHOU2 ; XINRU WANG2 ; QIZHAN LIU1 2
[1] Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu, China
[2] The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu, China
[3] Qujing Center for Disease Control and Prevention, Qujing 655000, Yunnan, China - Source
Toxicology and applied pharmacology. 2013, Vol 266, Num 2, pp 187-197, 11 p ; ref : 3/4 p
- CODEN
- TXAPA9
- ISSN
- 0041-008X
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Arsenite Biphasic effects Extracellular signal-regulated kinases (ERK) Hypoxia inducible factor-1α Hypoxia inducible factor-2α c-Jun N-terminal kinases (JNK)
- Keyword (fr)
- Accumulation biologique Arsénite Bronche Cellule épithéliale Extracellular signal-regulated protein kinase Facteur transcription HIF1 Homme In vitro Mitogen-activated protein kinase Facteur de transcription HIF2 alpha c-Jun N-terminal kinase Appareil respiratoire Enzyme Transferases Voie respiratoire
- Keyword (en)
- Biological accumulation Arsenites Bronchus Epithelial cell Extracellular signal-regulated protein kinase Transcription factor HIF1 Human In vitro Mitogen-activated protein kinase Hypoxia inducible transcription factor 2 alpha Respiratory system Enzyme Transferases Respiratory tract
- Keyword (es)
- Acumulación biológica Arsenito Bronquio Célula epitelial Extracellular signal-regulated protein kinase Factor transcripción HIF1 Hombre In vitro Mitogen-activated protein kinase Aparato respiratorio Enzima Transferases Vía respiratoria
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L05 Metals and various inorganic compounds
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26898274
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.taap.2012.11.014 
https://dx.doi.org/10.1016/j.taap.2012.11.014
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